Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. (Q42801345)

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4 November 2019

title

Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase (English)

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4 November 2019

11

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4 November 2019

Francesco Andreozzi

1

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4 November 2019

Rosa Marina Melillo

2

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Maria Domenica Castellone

4 November 2019

8

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4 November 2019

author name string

Francesca Carlomagno

3

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4 November 2019

Francesco Oriente

4

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4 November 2019

Claudia Miele

5

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4 November 2019

Francesca Fiory

6

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4 November 2019

Stefania Santopietro

7

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4 November 2019

Francesco Beguinot

9

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4 November 2019

Massimo Santoro

10

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4 November 2019

language of work or name

English

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publication date

1 May 2003

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4 November 2019

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4 November 2019

volume

22

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4 November 2019

issue

19

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4 November 2019

page(s)

2942-2949

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Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

4 November 2019

cites work

1 reference

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Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells

21 January 2018

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In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing

21 January 2018

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Insulin receptor substrate-2 phosphorylation is necessary for protein kinase C zeta activation by insulin in L6hIR cells

21 January 2018

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Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway.

21 January 2018

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Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells

21 January 2018

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The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

21 January 2018

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7 January 2021

Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.

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7 January 2021

Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism

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7 January 2021

Effects of Epidermal Growth Factor and 12-O-Tetradecanoylphorbol-13-Acetate on Metabolism of the Epidermal Growth Factor Receptor in Normal Human Fibroblasts

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7 January 2021

Autophosphorylation sites on the epidermal growth factor receptor.

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7 January 2021

Perspective: lessons learned from molecular genetic studies of thyroid cancer--insights into pathogenesis and tumor-specific therapeutic targets

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7 January 2021

Mechanisms whereby insulin increases diacylglycerol in BC3H-1 myocytes

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7 January 2021

Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells.

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7 January 2021

Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase

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7 January 2021

Protein kinase C isozymes and substrates

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7 January 2021

The RET proto-oncogene in human cancers

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7 January 2021

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

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7 January 2021

Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation

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7 January 2021

The RET receptor: function in development and dysfunction in congenital malformation

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7 January 2021

The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.

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7 January 2021

Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

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7 January 2021

The extended protein kinase C superfamily

1 reference

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7 January 2021

Regulation of protein kinase C.

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7 January 2021

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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7 January 2021

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

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7 January 2021

An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway

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7 January 2021

Rapid and Long Term Effects of Protein Kinase C on Receptor Tyrosine Kinase Phosphorylation and Degradation

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7 January 2021

Protein kinase C mediates short- and long-term effects on receptor tyrosine kinases. Regulation of tyrosine phosphorylation and degradation

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7 January 2021

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12771945%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 November 2019

1002784691

0 references

1 reference