IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress (Q42801707)

7 November 2017

IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress (English)

1 reference

7 November 2017

1 reference

1 reference

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1097-5

3 January 2024

4

A. Rudich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750770

3 January 2024

author name string

R. Potashnik

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750770

3 January 2024

A. Bloch-Damti

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750770

3 January 2024

N. Bashan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750770

3 January 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12750770

3 January 2024

publication date

15 May 2003

1 reference

full work available at URL

7 November 2017

https://link.springer.com/content/pdf/10.1007/s00125-003-1097-5.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750770

http://link.springer.com/content/pdf/10.1007/s00125-003-1097-5.pdf

3 January 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1097-5

http://link.springer.com/article/10.1007/s00125-003-1097-5/fulltext.html

3 January 2024

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1097-5

http://link.springer.com/content/pdf/10.1007/s00125-003-1097-5

3 January 2024

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1097-5

3 January 2024

1 reference

7 November 2017

46

1 reference

7 November 2017

639-648

1 reference

7 November 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1007/s00125-003-1097-5

7 November 2017

0 references

cites work

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Oxidative stress impairs nuclear proteins binding to the insulin responsive element in the GLUT4 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Redox control of protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Insulin stimulates the degradation of IRS-1 in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Release of insulin receptor substrate proteins from an intracellular complex coincides with the development of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

The insulin-induced down-regulation of IRS-1 in 3T3-L1 adipocytes is mediated by a calcium-dependent thiol protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1097-5

Oxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytes

21 January 2018

1 reference

12 December 2020

The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells

1 reference

12 December 2020

Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes

1 reference

12 December 2020

Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes.

1 reference

12 December 2020

Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM.

1 reference

12 December 2020

Insulin resistance: a phosphorylation-based uncoupling of insulin signaling

1 reference

12 December 2020

Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase

1 reference

12 December 2020

Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells

1 reference

12 December 2020

Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated

1 reference

12 December 2020

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function

1 reference

12 December 2020

American Journal of Physiology

33

272

E935

Rudich

1997

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1097-5

3 January 2024

Identifiers

1 reference

7 November 2017

1 reference