PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression (Q42808879)

7 November 2017

PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression (English)

1 reference

7 November 2017

Lei Zhang

1

1 reference

PubMed ID

12401804

7 November 2017

Chiayeng Wang

series ordinal

2

1 reference

PubMed ID

12401804

7 November 2017

language of work or name

English

0 references

publication date

24 October 2002

1 reference

Journal of Biological Chemistry

7 November 2017

1 reference

7 November 2017

278

1 reference

7 November 2017

1

1 reference

7 November 2017

27-36

1 reference

Childhood cancer incidence: Geographical and temporal variations

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Histopathology of childhood sarcomas, Intergroup Rhabdomyosarcoma Studies I and II: clinicopathologic correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Pax: gene regulators in the developing nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The hepatocyte nuclear factor-3/forkhead transcription regulatory family in development, inflammation, and neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Pax-3 contains domains for transcription activation and transcription inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The COOH-terminal transactivation domain plays a key role in regulating the in vitro and in vivo function of Pax3 homeodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Anchorage-dependent cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Expression of the v-Src oncoprotein in fibroblasts disrupts normal regulation of the CDK inhibitor p27 and inhibits quiescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Inhibition of DNA synthesis by downregulation of cyclin A but not Skp 2 overexpression in human hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Pax3 inhibits myogenic differentiation of cultured myoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Incidence of malignant tumors in U.S. children

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Molecular differential pathology of rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Rhabdomyosarcoma: a clinicopathological study and classification of 39 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Consistent chromosomal translocation in alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

Transcriptional regulation of IGF-I receptor gene expression by the PAX3-FKHR oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205424200

21 January 2018

Identifiers

DOI

10.1074/JBC.M205424200

1 reference

7 November 2017

1 reference

PubMed ID

12401804