PAX6, paired domain influences sequence recognition by the homeodomain (Q42809226)

7 November 2017

PAX6, paired domain influences sequence recognition by the homeodomain (English)

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7 November 2017

Rajnikant Mishra

1

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7 November 2017

Ivan P Gorlov

2

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7 November 2017

Lian Y Chao

3

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7 November 2017

Sanjaya Singh

4

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7 November 2017

Grady F Saunders

5

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7 November 2017

language of work or name

English

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publication date

17 October 2002

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

277

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7 November 2017

51

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7 November 2017

49488-49494

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Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Lens induction by Pax-6 in Xenopus laevis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Pax 6: mastering eye morphogenesis and eye evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Pax6 is required for the multipotent state of retinal progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Helix 2 of the paired domain plays a key role in the regulation of DNA-binding by the Pax-3 homeodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

PAX6 missense mutation in isolated foveal hypoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Functional analysis of paired box missense mutations in the PAX6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

21 January 2018

PAX6 mutations reviewed

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Mutational analysis of PAX6: 16 novel mutations including 5 missense mutations with a mild aniridia phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Missense mutations in the most ancient residues of the PAX6 paired domain underlie a spectrum of human congenital eye malformations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Mutation in the PAX6 gene in twenty patients with aniridia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

PAX6 mutation in a family with aniridia, congenital ptosis, and mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

PAX6 in sensory development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Getting your Pax straight: Pax proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Pax3 modulates expression of the c-Met receptor during limb muscle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Molecular basis of splotch and Waardenburg Pax-3 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Homeodomain-DNA recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Vertebrate eye development as modeled in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

The eyeless homeodomain is dispensable for eye development in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Cooperative dimerization of paired class homeo domains on DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Mouse small eye results from mutations in a paired-like homeobox-containing gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Modulation of PAX6 homeodomain function by the paired domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

A new set of primers for mutation analysis of the human PAX6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

A method for obtaining reporter gene activity and nuclear extracts simultaneously from transiently transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Lens-specific gene recruitment of zeta-crystallin through Pax6, Nrl-Maf, and brain suppressor sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Characterization of quail Pax-6 (Pax-QNR) proteins expressed in the neuroretina

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Truncation mutations in the transactivation region of PAX6 result in dominant-negative mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Ten novel mutations found in Aniridia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

A novel PAX6 gene mutation (P118R) in a family with congenital nystagmus associated with a variant form of aniridia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

Autoregulation of Pax6 transcriptional activation by two distinct DNA-binding subdomains of the paired domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206478200

21 January 2018

Identifiers

DOI

10.1074/JBC.M206478200

1 reference

7 November 2017

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