Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes (Q42817543)

7 November 2017

title

Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes (English)

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7 November 2017

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5

Jerrold M Olefsky

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7 November 2017

Satoshi Ugi

1

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7 November 2017

Prem M Sharma

series ordinal

2

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7 November 2017

William Ricketts

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3

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7 November 2017

Takeshi Imamura

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4

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7 November 2017

language of work or name

English

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publication date

15 March 2002

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

277

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7 November 2017

issue

21

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7 November 2017

page(s)

18592-18597

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Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

7 November 2017

cites work

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Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

21 January 2018

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1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

21 January 2018

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Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

21 January 2018

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Functional interactions of phosphatidylinositol 3-kinase with GTPase-activating protein in 3T3-L1 adipocytes.

21 January 2018

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Differential activation of mitogen-activated protein kinase by insulin and epidermal growth factor in 3T3-L1 adipocytes: a possible involvement of PI3-kinase in the activation of the MAP kinase by insulin

21 January 2018

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Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action

21 January 2018

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Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways

21 January 2018

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

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Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling

21 January 2018

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Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo

21 January 2018

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Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling

21 January 2018

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Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

21 January 2018

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

21 January 2018

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Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo

21 January 2018

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A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

21 January 2018

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Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes

21 January 2018

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Shc Phosphotyrosine-Binding Domain Dominantly Interacts with Epidermal Growth Factor Receptors and Mediates Ras Activation in Intact Cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201019200

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7 November 2017

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