Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto-Kakizaki rat model of type 2 diabetes (Q42828699)

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scientific article published on 3 May 2007

Language	Label	Description	Also known as
English	Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto-Kakizaki rat model of type 2 diabetes	scientific article published on 3 May 2007

Statements

scholarly article

1 reference

Europe PubMed Central

8 November 2017

Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto-Kakizaki rat model of type 2 diabetes (English)

1 reference

Europe PubMed Central

8 November 2017

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type 2 diabetes

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based on heuristic

inferred from title

Carmen Álvarez

6

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Europe PubMed Central

8 November 2017

author name string

S Calderari

1

1 reference

Europe PubMed Central

8 November 2017

M-N Gangnerau

2

1 reference

Europe PubMed Central

8 November 2017

M Thibault

3

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Europe PubMed Central

8 November 2017

M-J Meile

4

1 reference

Europe PubMed Central

8 November 2017

N Kassis

5

1 reference

Europe PubMed Central

8 November 2017

B Portha

7

1 reference

Europe PubMed Central

8 November 2017

P Serradas

8

1 reference

Europe PubMed Central

8 November 2017

publication date

3 May 2007

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Europe PubMed Central

8 November 2017

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Europe PubMed Central

8 November 2017

50

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Europe PubMed Central

8 November 2017

1463-1471

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Europe PubMed Central

8 November 2017

7

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Europe PubMed Central

8 November 2017

https://scigraph.springernature.com/pub.10.1007/s00125-007-0676-2

0 references

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-007-0676-2

21 January 2018

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-caloric food restriction affects insulin-like growth factor system in fetal Wistar rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of undernutrition and diabetes on serum and liver mRNA expression of IGFs and their binding proteins during rat development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental aspects of the endocrine pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into the roles of insulin/IGF-I in the development and maintenance of beta-cell mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of spontaneous diabetic rats by repetition of selective breeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired pancreatic beta cell function in the fetal GK rat. Impact of diabetic inheritance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial deoxyribonucleic acid content is specifically decreased in adult, but not fetal, pancreatic islets of the Goto-Kakizaki rat, a genetic model of noninsulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of cell survival by IGF signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular distribution and ontogeny of insulin-like growth factors (IGFs) and IGF binding protein messenger RNAs and peptides in developing rat pancreas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phylogeny of the insulin-like growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early development of beta-cells is impaired in the GK rat model of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factors and their binding proteins: biological actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ultrastructural analysis of the developing embryonic pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of insulin-like growth factors in development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal insulin-like growth factor-2 production is impaired in the GK rat model of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell mass depletion precedes the onset of hyperglycaemia in the GK rat, a genetic model of non-insulin-dependent diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for VPAC2 receptor-mediated signals in pancreas development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The life story of the pancreatic B cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IRS proteins and beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of glucose on beta cells in pancreatic monolayer cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors and the regulation of fetal growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of extraction methods for insulin-like growth factor-binding proteins prior to measurement of insulin-like growth factor-I in undernourished neonatal and adult rat serum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17476475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-007-0676-2

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

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