MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain. (Q42828942)

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17 February 2020

title

MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain (English)

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17 February 2020

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stem cell differentiation

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3

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17 February 2020

author name string

Siok-Lay Tan

series ordinal

1

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17 February 2020

Toshiyuki Ohtsuka

series ordinal

2

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17 February 2020

Ryoichiro Kageyama

series ordinal

4

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17 February 2020

publication date

8 November 2012

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17 February 2020

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17 February 2020

volume

17

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17 February 2020

issue

12

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17 February 2020

page(s)

952-961

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Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system.

17 February 2020

cites work

1 reference

Dynamic expression and essential functions of Hes7 in somite segmentation

21 January 2018

1 reference

MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis

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MicroRNA-9 Modulates Hes1 ultradian oscillations by forming a double-negative feedback loop

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miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

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MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors

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MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma

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Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation

21 January 2018

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MicroRNAs: small RNAs with a big role in gene regulation

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Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop

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Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline

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Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects

21 January 2018

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The Hes gene family: repressors and oscillators that orchestrate embryogenesis

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The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells

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MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary

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The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease

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The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning

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