The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system (Q42835180)

8 November 2017

The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system (English)

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8 November 2017

endoplasmic reticulum

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author

Uri Mbonye

1

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8 November 2017

Masayuki Wada

2

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8 November 2017

Caroline J Rieke

3

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8 November 2017

Hui-Yuan Tang

4

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8 November 2017

David L Dewitt

5

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8 November 2017

William L Smith

6

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8 November 2017

language of work or name

English

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publication date

25 September 2006

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

281

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8 November 2017

47

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8 November 2017

35770-35778

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Genetic and pharmacological analysis of prostanoid receptor function

8 November 2017

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The cyclooxygenase reaction mechanism

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Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases

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The role of prostaglandins and other eicosanoids in the gastrointestinal tract

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Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

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Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis

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Comparison of structural stabilities of prostaglandin H synthase-1 and -2.

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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

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Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy

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The membrane binding domains of prostaglandin endoperoxide H synthases 1 and 2. Peptide mapping and mutational analysis

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Prostaglandin synthase 2.

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Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes

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Prostaglandin G/H synthase isoenzyme 2 expression in fibroblasts: regulation by dexamethasone, mitogens, and oncogenes

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Proteasome inhibition in neuronal cells induces a proinflammatory response manifested by upregulation of cyclooxygenase-2, its accumulation as ubiquitin conjugates, and production of the prostaglandin PGE(2).

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N-acetylcysteine and celecoxib lessen cadmium cytotoxicity which is associated with cyclooxygenase-2 up-regulation in mouse neuronal cells

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For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection

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Retrograde protein translocation: ERADication of secretory proteins in health and disease

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

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Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).

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Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

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ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

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Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

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Role of N-linked polymannose oligosaccharides in targeting glycoproteins for endoplasmic reticulum-associated degradation

21 January 2018

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ERAD: the long road to destruction

21 January 2018

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Different suicide inactivation processes for the peroxidase and cyclooxygenase activities of prostaglandin endoperoxide H synthase-1.

21 January 2018

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Purification and characterization of recombinant human prostacyclin synthase

21 January 2018

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Redundancy in the signaling pathways and promoter elements regulating cyclooxygenase-2 gene expression in endotoxin-treated macrophage/monocytic cells

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Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids

21 January 2018

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Characterization of the glycosylation sites in cyclooxygenase-2 using mass spectrometry

21 January 2018

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Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I.

21 January 2018

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Glycoprotein quality control in the endoplasmic reticulum. Mannose trimming by endoplasmic reticulum mannosidase I times the proteasomal degradation of unassembled immunoglobulin subunits

21 January 2018

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Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.

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Characterization of endoplasmic reticulum-associated degradation of a protein S mutant identified in a family of quantitative protein S deficiency

21 January 2018

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Processing of N-linked glycans during endoplasmic-reticulum-associated degradation of a short-lived variant of ribophorin I.

21 January 2018

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A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

21 January 2018

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Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region

21 January 2018

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The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

21 January 2018

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Ubiquitin-dependent 26S proteasomal pathway: a role in the degradation of native human liver CYP3A4 expressed in Saccharomyces cerevisiae?

21 January 2018

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Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+

21 January 2018

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A novel role for N-glycans in the ERAD system

21 January 2018

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Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation

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EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

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A C-terminal signal prevents secretion of luminal ER proteins

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21 January 2018

Identifiers

DOI

10.1074/JBC.M608281200

1 reference

8 November 2017

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