Pharmacogenetic interaction analysis for the efficacy of systemic treatment in metastatic colorectal cancer. (Q42837601)

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15 January 2020

title

Pharmacogenetic interaction analysis for the efficacy of systemic treatment in metastatic colorectal cancer (English)

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15 January 2020

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6

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15 January 2020

author name string

J Pander

1

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15 January 2020

J A M Wessels

2

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15 January 2020

H Gelderblom

3

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15 January 2020

T van der Straaten

4

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15 January 2020

C J A Punt

5

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15 January 2020

language of work or name

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3 November 2010

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15 January 2020

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15 January 2020

volume

22

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15 January 2020

issue

5

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15 January 2020

page(s)

1147-1153

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Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer

15 January 2020

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Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study.

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Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

21 January 2018

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Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil.

21 January 2018

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity

21 January 2018

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Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients

21 January 2018

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Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer

21 January 2018

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients.

21 January 2018

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Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer

21 January 2018

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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

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A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

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A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

21 January 2018

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Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial

21 January 2018

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Glutathione-S-transferase pi (GSTP1) codon 105 polymorphism is not associated with oxaliplatin efficacy or toxicity in advanced colorectal cancer patients

21 January 2018

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Determination of ERCC2 Lys751Gln and GSTP1 Ile105Val gene polymorphisms in colorectal cancer patients: relationships with treatment outcome

21 January 2018

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Single nucleotide polymorphisms in nucleotide excision repair genes XPA, XPD, XPG and ERCC1 in advanced colorectal cancer patients treated with first-line oxaliplatin/fluoropyrimidine

21 January 2018

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Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy

21 January 2018

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Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer

21 January 2018

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ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer.

21 January 2018

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A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues

21 January 2018

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Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution

21 January 2018

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Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100.

21 January 2018

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A common 936 C/T gene polymorphism of vascular endothelial growth factor is associated with decreased breast cancer risk.

21 January 2018

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A common 936 C/T mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels

21 January 2018

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Replication validity of genetic association studies

21 January 2018

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Combinatorial pharmacogenetics

21 January 2018

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The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

21 January 2018

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A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

21 January 2018

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Insights into the role of heritable genetic variation in the pharmacokinetics and pharmacodynamics of anticancer drugs

21 January 2018

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Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy?

21 January 2018

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Pharmacogenetics of EGFR and VEGF inhibition

21 January 2018

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Genome-wide association studies for complex traits: consensus, uncertainty and challenges

21 January 2018

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A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

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Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans

21 January 2018

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A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?

21 January 2018

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Angiogenesis as a therapeutic target

21 January 2018

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5-Fluorouracil: mechanisms of action and clinical strategies

21 January 2018

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Genetic prognostic and predictive markers in colorectal cancer

21 January 2018

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Tumor Thymidylate Synthase 1494del6 Genotype As a Prognostic Factor in Colorectal Cancer Patients Receiving Fluorouracil-Based Adjuvant Treatment

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/ANNONC/MDQ572

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048041%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference