Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration. (Q42852989)

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8 February 2020

title

Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration (English)

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8 February 2020

1 reference

4

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8 February 2020

Jun Abe

5

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8 February 2020

Kei Sugihara

8

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8 February 2020

author name string

Makoto Kurachi

1

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8 February 2020

Junko Kurachi

2

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8 February 2020

Fumiko Suenaga

3

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8 February 2020

Satoshi Ueha

6

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8 February 2020

Michio Tomura

7

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8 February 2020

Shiki Takamura

9

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8 February 2020

Kazuhiro Kakimi

10

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8 February 2020

Kouji Matsushima

11

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8 February 2020

language of work or name

English

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publication date

25 July 2011

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Journal of Experimental Medicine

8 February 2020

published in

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8 February 2020

volume

208

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8 February 2020

page(s)

1605-1620

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8 February 2020

issue

8

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Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection.

8 February 2020

cites work

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Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation

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Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation

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27 May 2018

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Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

27 May 2018

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27 May 2018

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T cell extravasation: demonstration of synergy between activation of CXCR3 and the T cell receptor.

27 May 2018

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Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses

27 May 2018

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Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

27 May 2018

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A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation.

27 May 2018

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CXCR3 deficiency increases susceptibility to genital herpes simplex virus type 2 infection: Uncoupling of CD8+ T-cell effector function but not migration

27 May 2018

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mTOR regulates memory CD8 T-cell differentiation

27 May 2018

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Enhancing CD8 T-cell memory by modulating fatty acid metabolism

27 May 2018

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Programming for CD8 T cell memory development requires IL-12 or type I IFN

27 May 2018

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Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation

27 May 2018

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CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality

27 May 2018

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Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence

27 May 2018

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Orchestrating the orchestrators: chemokines in control of T cell traffic

27 May 2018

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The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor.

27 May 2018

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27 May 2018

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CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection

27 May 2018

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Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

27 May 2018

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Chemokine receptor CXCR3: an unexpected enigma

27 May 2018

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27 May 2018

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Initial T cell frequency dictates memory CD8+ T cell lineage commitment

27 May 2018

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27 May 2018

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

27 May 2018

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Lineage relationship and protective immunity of memory CD8 T cell subsets

27 May 2018

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27 May 2018

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IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking

27 May 2018

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27 May 2018

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27 May 2018

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T cells compete for access to antigen-bearing antigen-presenting cells

27 May 2018

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27 May 2018

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27 May 2018

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Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection

27 May 2018

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27 May 2018

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Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

16 August 2018

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16 August 2018

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Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

16 August 2018

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Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.

16 August 2018

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T cells use two directionally distinct pathways for cytokine secretion.

16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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Splenic marginal metallophilic macrophages and marginal zone macrophages are the major interferon-alpha/beta producers in mice upon intravenous challenge with herpes simplex virus

16 August 2018

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What messenger RNA capping tells us about eukaryotic evolution.

16 August 2018

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Regulation of Homeostatic Chemokine Expression and Cell Trafficking During Immune Responses

21 January 2018

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Cutting edge: stromal cell-derived factor-1 is a costimulator for CD4+ T cell activation

21 January 2018

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12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

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12 December 2020

Marginal zone macrophages and immune responses against viruses

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12 December 2020

Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction

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12 December 2020

Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro

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12 December 2020

Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation

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12 December 2020

Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation

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12 December 2020

Maintenance of memory CD8+ T cell diversity and proliferative potential by a primary response upon re-challenge

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Identifiers

DOI

10.1084/JEM.20102101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21788406%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21788406%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference