Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal (Q42857041)

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scientific article published on November 2006

Language	Label	Description	Also known as
English	Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal	scientific article published on November 2006

Statements

scholarly article

1 reference

Europe PubMed Central

8 November 2017

Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal (English)

1 reference

Europe PubMed Central

8 November 2017

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6

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Douglas D. Redelman

2

object named as

Doug Redelman

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author name string

David L Tamang

1

1 reference

Europe PubMed Central

8 November 2017

Bryce N Alves

3

1 reference

Europe PubMed Central

8 November 2017

Leanne Vollger

4

1 reference

Europe PubMed Central

8 November 2017

Christy Bethley

5

1 reference

Europe PubMed Central

8 November 2017

publication date

1 November 2006

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

36

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Europe PubMed Central

8 November 2017

148-159

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Europe PubMed Central

8 November 2017

3-4

1 reference

Europe PubMed Central

8 November 2017

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850105

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IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation

1 reference

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CD69 is an immunoregulatory molecule induced following activation

1 reference

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IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21

1 reference

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Interleukin-2 improves tumour response to DNP-modified autologous vaccine for the treatment of metastatic malignant melanoma

1 reference

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IL-15 is a growth factor and an activator of CD8 memory T cells

1 reference

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

1 reference

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The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases

1 reference

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IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells

1 reference

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The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

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PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

1 reference

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Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

1 reference

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In vivo tracking of tumor-specific T cells

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Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice

1 reference

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What to do with IL-2?

1 reference

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Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand

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Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

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Role of co-stimulation in CD8+ T cell activation.

1 reference

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Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

1 reference

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CD2 rescues T cells from T-cell receptor/CD3 apoptosis: a role for the Fas/Fas-L system.

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Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells

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Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells

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Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

1 reference

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In vivo regulation of murine granzyme B gene transcription in activated primary T cells

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Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes

1 reference

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Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

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Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

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Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chains

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Differential T cell costimulatory requirements in CD28-deficient mice

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CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.

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Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor

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Clinical applications of IL-2.

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IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.

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Identifiers

10.1016/J.CYTO.2006.11.008

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

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