An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells (Q42860831)

8 November 2017

An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells (English)

1 reference

8 November 2017

1 reference

1 reference

4

1 reference

PMC publication ID

4154298

8 November 2017

Alfonso Martinez Arias

series ordinal

5

object named as

Alfonso Martinez Arias

1 reference

8 November 2017

1

David A Turner

1 reference

8 November 2017

3

Penelope Hayward

1 reference

8 November 2017

Jamie Trott

2

1 reference

8 November 2017

20 June 2014

1 reference

8 November 2017

1 reference

8 November 2017

3

1 reference

8 November 2017

7

1 reference

8 November 2017

614-626

1 reference

Creative Commons Attribution 3.0 Unported

8 November 2017

start time

2 September 2020

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Brachyury cooperates with Wnt/β-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells

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Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors.

27 May 2018

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Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin.

27 May 2018

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A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells

27 May 2018

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Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog

27 May 2018

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A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages

27 May 2018

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Quantitative transcriptomics using designed primer-based amplification

27 May 2018

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Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

27 May 2018

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A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells

27 May 2018

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Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation

27 May 2018

1 reference

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In vitro organogenesis in three dimensions: self-organising stem cells

27 May 2018

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TGF-β-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium

27 May 2018

1 reference

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Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations

27 May 2018

1 reference

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Correlations between the levels of Oct4 and Nanog as a signature for naïve pluripotency in mouse embryonic stem cells

27 May 2018

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Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules.

27 May 2018

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Initiating head development in mouse embryos: integrating signalling and transcriptional activity

27 May 2018

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Fiji: an open-source platform for biological-image analysis

27 May 2018

1 reference

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The structure of Wntch signalling and the resolution of transition states in development.

27 May 2018

1 reference

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Gene expression heterogeneities in embryonic stem cell populations: origin and function

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Distinct developmental ground states of epiblast stem cell lines determine different pluripotency features

27 May 2018

1 reference

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Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal

27 May 2018

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Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Pluripotency factors in embryonic stem cells regulate differentiation into germ layers

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

27 May 2018

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Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells

27 May 2018

1 reference

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Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

RNA-Seq analysis to capture the transcriptome landscape of a single cell

27 May 2018

1 reference

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Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

27 May 2018

How to make beta cells?

1 reference

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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

27 May 2018

1 reference

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Neural differentiation of embryonic stem cells in vitro: a road map to neurogenesis in the embryo

27 May 2018

1 reference

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Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.

27 May 2018

1 reference

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Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

The ground state of embryonic stem cell self-renewal

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Nanog safeguards pluripotency and mediates germline development

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

BMP signalling inhibits premature neural differentiation in the mouse embryo

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Proposal of a model of mammalian neural induction

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Gene expression pattern and progression of embryogenesis in the immediate post-implantation period of mouse development

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Filtering transcriptional noise during development: concepts and mechanisms

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Germ layer induction from embryonic stem cells.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Directed differentiation of telencephalic precursors from embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Beta-catenin signaling is required for neural differentiation of embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Development of definitive endoderm from embryonic stem cells in culture

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Changing potency by spontaneous fusion.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Embryo-derived stem cells: of mice and men.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

BMP-4 inhibits neural differentiation of murine embryonic stem cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Axis development and early asymmetry in mammals

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

The positional identity of mouse ES cell-generated neurons is affected by BMP signaling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

A precarious balance: pluripotency factors as lineage specifiers.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

The origin and identity of embryonic stem cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Neural induction intermediates exhibit distinct roles of Fgf signaling.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Retinoic Acid Synthesis Promotes Development of Neural Progenitors from Mouse Embryonic Stem Cells by Suppressing Endogenous, Wnt-Dependent Nodal Signaling

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Distinct functions of BMP4 during different stages of mouse ES cell neural commitment.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

Anterior patterning in mouse.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154298

[In vitro differentiation of telencephalic precursors from ES cells]

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24950969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression Profiles of Wnt Genes during Neural Differentiation of Mouse Embryonic Stem Cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24950969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24950969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/BIO.20148409

1 reference

8 November 2017

1 reference

PMC publication ID

4154298

8 November 2017

PubMed publication ID

24950969

1 reference

PMC publication ID

4154298