Allosteric rescuing of loss-of-function FFAR2 mutations (Q42909032)

10 November 2017

Allosteric rescuing of loss-of-function FFAR2 mutations (English)

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10 November 2017

7

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10 November 2017

Gayathri Swaminath

1

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10 November 2017

Peter Jaeckel

2

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10 November 2017

Qi Guo

3

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10 November 2017

Mario Cardozo

4

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10 November 2017

Jennifer Weiszmann

5

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10 November 2017

Richard Lindberg

6

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10 November 2017

Ralf Schwandner

8

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10 November 2017

Yang Li

9

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10 November 2017

language of work or name

English

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publication date

17 September 2010

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10 November 2017

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10 November 2017

584

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19

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10 November 2017

4208-4214

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A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1

10 November 2017

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

Fatty acid receptors as new therapeutic targets for diabetes

21 January 2018

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The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

21 January 2018

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Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids

21 January 2018

1 reference

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Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

21 January 2018

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Fatty acid binding receptors and their physiological role in type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

Bidirectional, iterative approach to the structural delineation of the functional "chemoprint" in GPR40 for agonist recognition

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

Identification of residues important for agonist recognition and activation in GPR40

21 January 2018

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Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids

21 January 2018

1 reference

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Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2.

21 January 2018

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A hierarchical approach to all-atom protein loop prediction

21 January 2018

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

21 January 2018

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

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Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)

21 January 2018

1 reference

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Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation.

21 January 2018

1 reference

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The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

21 January 2018

1 reference

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Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox

21 January 2018

1 reference

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Allosteric Modulation of G Protein–Coupled Receptors

21 January 2018

1 reference

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Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity

21 January 2018

1 reference

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An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

21 January 2018

1 reference

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Structural determinants of allosteric agonism and modulation at the M4 muscarinic acetylcholine receptor: identification of ligand-specific and global activation mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.09.007

10.1016/J.FEBSLET.2010.09.007

21 January 2018

Identifiers

DOI

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10 November 2017

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