The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity (Q42933552)

11 November 2017

The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity (English)

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11 November 2017

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Wing Lam

1

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11 November 2017

Scott Bussom

2

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11 November 2017

Fulan Guan

3

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11 November 2017

Zaoli Jiang

4

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11 November 2017

Wei Zhang

5

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11 November 2017

Elizabeth A Gullen

6

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11 November 2017

Shwu-Huey Liu

7

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11 November 2017

Yung-Chi Cheng

8

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11 November 2017

language of work or name

English

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publication date

1 August 2010

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Science Translational Medicine

11 November 2017

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11 November 2017

2

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11 November 2017

45

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11 November 2017

45ra59

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Phase I/IIA randomized study of PHY906, a novel herbal agent, as a modulator of chemotherapy in patients with advanced colorectal cancer

11 November 2017

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Irinotecan (CPT-11) and characteristic mucosal changes in the mouse ileum and cecum.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Oral RDP58 allows CPT-11 dose intensification for enhanced tumor response by decreasing gastrointestinal toxicity

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Identification of stem cells in small intestine and colon by marker gene Lgr5

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Bmi1 is expressed in vivo in intestinal stem cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Involvement of Nuclear Factor-κB in the Inhibition of Interleukin-12 Production from Mouse Macrophages by Baicalein, a Flavonoid inScutellaria baicalensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Wogonin inhibits inducible prostaglandin E(2) production in macrophages

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Nitric oxide-modulating agents for gastrointestinal disorders

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Mitogenic influence of human R-spondin1 on the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

A new nuclear component of the Wnt signalling pathway

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

Phase I study of the botanical formulation PHY906 with capecitabine in advanced pancreatic and other gastrointestinal malignancies

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3001270

10.1126/SCITRANSLMED.3001270

21 January 2018

Identifiers

DOI

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11 November 2017

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