A human immunoglobulin lambda locus is similarly well expressed in mice and humans (Q42944671)

11 November 2017

A human immunoglobulin lambda locus is similarly well expressed in mice and humans (English)

1 reference

11 November 2017

A V Popov

1

1 reference

11 November 2017

X Zou

2

1 reference

11 November 2017

J Xian

3

1 reference

11 November 2017

I C Nicholson

4

1 reference

11 November 2017

M Brüggemann

5

1 reference

11 November 2017

language of work or name

English

0 references

publication date

1 May 1999

1 reference

Journal of Experimental Medicine

11 November 2017

1 reference

11 November 2017

189

1 reference

11 November 2017

10

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11 November 2017

1611-1620

1 reference

Propagation in a fluid medium of a human epidermoid carcinoma, strain KB.

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

The immunoglobulin lambda light chain enhancer consists of three modules which synergize in activation of transcription

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Regulation of B cell development by variable gene complexity in mice reconstituted with human immunoglobulin yeast artificial chromosomes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

The creation of diversity in the human immunoglobulin V(lambda) repertoire

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

One-megabase sequence analysis of the human immunoglobulin lambda gene locus

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Sequence and evolution of the human germline V lambda repertoire

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

The human lambda immunoglobulin enhancer is controlled by both positive elements and developmentally regulated negative elements

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

1 Preparation of monoclonal antibodies: Strategies and procedures

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

On the mechanism of antibody synthesis: a species comparison of L-chains

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Immunoglobulin lambda gene rearrangement can precede kappa gene rearrangement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Murine lambda gene rearrangements: the stochastic model prevails over the ordered model

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14 kb and rearrange by a deletion mechanism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Re-organization of the immunoglobulin kappa gene on both alleles is not an obligatory prerequisite for Ig lambda gene expression in human cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Dominant expression of a 1.3 Mb human Ig kappa locus replacing mouse light chain production.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Tissue-specific deoxyribonuclease I-hypersensitive sites in the vicinity of the immunoglobulin C lambda cluster of man.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Subtle differences in antibody responses and hypermutation of lambda light chains in mice with a disrupted chi constant region

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Estimate of the light chain repertoire size of fetal and adult BALB/cJ and CBA/J mice.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

IMGT, the international ImMunoGeneTics database

16 August 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Immunohistochemical examination of light-chain expression (lambda/kappa ratio) in canine, feline, equine, bovine and porcine plasma cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193639

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

3 November 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Variable amplification of immunoglobulin λ light-chain genes in human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Lambda chain expression at different stages of ontogeny in C57BL/6, BALB/c and SJL mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

The kappa/lambda ratio in surface immunoglobulin molecules on B lymphocytes differentiating from DHJH-rearranged murine pre-B cell clones in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Murine B lymphopoiesis: towards a unified model

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Re-evaluation of the probabilities for productive rearrangements on the κ andλloci

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Assembly and extension of yeast artificial chromosomes to build up a large locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1611

Reference values for immunoglobulin kappa and lambda light chains and the kappa/lambda ratio in children's serum

21 January 2018

1 reference

12 December 2020

Limited junctional diversity in kappa light chains. Junctional sequences from CD43+B220+ early B cell progenitors resemble those from peripheral B cells

1 reference

12 December 2020

Strategies for expressing human antibody repertoires in transgenic mice

1 reference

12 December 2020

kappa/lambda Shifts do not occur during maturation of murine B cells

1 reference

12 December 2020

Surface membrane kappa and lambda light chain expression on spleen cells of neonatal and maturing normal and immune-defective CBA/NB mice: the kappa:lambda ratio is constant

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.189.10.1611

1 reference

11 November 2017

1 reference

11 November 2017

PubMed publication ID

10330440

1 reference