Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis. (Q43099640)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482509%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis (English)

1 reference

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24 February 2020

12

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24 February 2020

Thibaud T. Renault

1

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24 February 2020

Konstantinos V Floros

2

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24 February 2020

Donald D Newmeyer

11

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24 February 2020

author name string

Rana Elkholi

3

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24 February 2020

Kelly-Ann Corrigan

4

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24 February 2020

Yulia Kushnareva

5

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24 February 2020

Shira Y Wieder

6

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24 February 2020

Claudia Lindtner

7

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24 February 2020

Madhavika N Serasinghe

8

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James J Asciolla

9

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24 February 2020

Christoph Buettner

10

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24 February 2020

publication date

4 December 2014

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24 February 2020

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24 February 2020

volume

57

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24 February 2020

issue

1

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24 February 2020

page(s)

69-82

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BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response

24 February 2020

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25 May 2018

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BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

25 May 2018

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25 May 2018

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Examining BCL-2 family function with large unilamellar vesicles

25 May 2018

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Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes

25 May 2018

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Mitochondrial fission, fusion, and stress

25 May 2018

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CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

25 May 2018

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Loss of mitofusin 2 promotes endoplasmic reticulum stress

25 May 2018

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Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis

25 May 2018

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Genetically defining the mechanism of Puma- and Bim-induced apoptosis

25 May 2018

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Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

25 May 2018

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Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization

25 May 2018

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Resistance to caspase-independent cell death requires persistence of intact mitochondria

25 May 2018

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25 May 2018

The BCL-2 family reunion

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Life and death of a BiP substrate

25 May 2018

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Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

25 May 2018

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Mitofusin 2 tethers endoplasmic reticulum to mitochondria

25 May 2018

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

25 May 2018

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IRE1 signaling affects cell fate during the unfolded protein response

25 May 2018

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ER stress triggers apoptosis by activating BH3-only protein Bim

25 May 2018

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Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

25 May 2018

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Structural and functional features and significance of the physical linkage between ER and mitochondria.

25 May 2018

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

25 May 2018

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

25 May 2018

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BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

25 May 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

25 May 2018

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Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis

25 May 2018

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Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

25 May 2018

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25 May 2018

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

25 May 2018

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

25 May 2018

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

25 May 2018

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25 May 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

25 May 2018

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Structure of Bax: coregulation of dimer formation and intracellular localization

25 May 2018

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Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

25 May 2018

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tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

25 May 2018

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Conformation of the Bax C-terminus regulates subcellular location and cell death

25 May 2018

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The stress response in Chinese hamster ovary cells. Regulation of ERp72 and protein disulfide isomerase expression and secretion.

25 May 2018

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Brefeldin A, thapsigargin, and AIF4- stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis

25 May 2018

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Cell Biology. Mitochondrial dynamics and apoptosis--the ER connection.

25 May 2018

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Expression, purification and use of recombinant annexin V for the detection of apoptotic cells

15 August 2018

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Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

15 August 2018

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15 August 2018

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Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity

15 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25482509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25482509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The ER function BiP is a master regulator of ER function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25482509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2014.10.028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482509%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482509%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482509%20AND%20SRC:MED&resulttype=core&format=json