BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response (Q34182014)

24074954

31 July 2017

title

BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response (English)

1 reference

31 July 2017

1 reference

Kristopher A Sarosiek

1

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31 May 2020

John Bachman

3

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31 May 2020

Joan Montero

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31 May 2020

David William Andrews

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31 May 2020

Peter K. Sorger

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31 May 2020

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Anthony Letai

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31 May 2020

author name string

Xiaoke Chi

2

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31 May 2020

Joshua J Sims

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31 May 2020

Luv Patel

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Annabelle Flanagan

7

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31 May 2020

publication date

1 September 2013

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31 July 2017

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31 May 2020

volume

51

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31 May 2020

issue

6

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31 May 2020

page(s)

751-765

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Direct activation of full-length proapoptotic BAK

31 May 2020

cites work

1 reference

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Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis

5 July 2018

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Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML

5 July 2018

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5 July 2018

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Molecular basis of the interaction between proapoptotic truncated BID (tBID) protein and mitochondrial carrier homologue 2 (MTCH2) protein: key players in mitochondrial death pathway

5 July 2018

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5 July 2018

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Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy

5 July 2018

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5 July 2018

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Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53.

5 July 2018

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5 July 2018

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Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway

5 July 2018

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MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

5 July 2018

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Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.

5 July 2018

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Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

5 July 2018

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Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy

5 July 2018

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BAX activation is initiated at a novel interaction site

5 July 2018

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BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

5 July 2018

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

5 July 2018

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A role for proapoptotic BID in the DNA-damage response

5 July 2018

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Etoposide, topoisomerase II and cancer

5 July 2018

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Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway

5 July 2018

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Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.

5 July 2018

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Bim is a suppressor of Myc-induced mouse B cell leukemia

5 July 2018

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DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling

5 July 2018

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Nonredundant role of Bax and Bak in Bid-mediated apoptosis

5 July 2018

1 reference

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

5 July 2018

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

5 July 2018

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Bax and Bak independently promote cytochrome C release from mitochondria

5 July 2018

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Apoptosis: a link between cancer genetics and chemotherapy

5 July 2018

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Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

5 July 2018

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Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

5 July 2018

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Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.

5 July 2018

1 reference

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Role of BAX in the apoptotic response to anticancer agents

5 July 2018

1 reference

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tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Functional CD95 ligand and CD95 death-inducing signaling complex in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Bim: a novel member of the Bcl-2 family that promotes apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Programmed cell death in animal development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Lethal effect of the anti-Fas antibody in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Proapoptotic BID is an ATM effector in the DNA-damage response

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4164233

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

28 October 2018

1 reference

12 December 2020

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

12 December 2020

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

12 December 2020

TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice

1 reference

12 December 2020

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

12 December 2020

Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice

1 reference

12 December 2020

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel

1 reference

12 December 2020

10.1016/J.MOLCEL.2013.08.048

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31 May 2020

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31 May 2020

24074954

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