Puma strikes Bax. (Q43107803)

14 November 2017

Puma strikes Bax. (English)

1 reference

14 November 2017

Anthony Letai

1

1 reference

PMCID

2700380

14 November 2017

language of work or name

English

0 references

publication date

1 April 2009

1 reference

14 November 2017

3

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

1 reference

14 November 2017

185

1 reference

14 November 2017

2

1 reference

14 November 2017

189-191

1 reference

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

14 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

BAX activation is initiated at a novel interaction site

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

The multidomain proapoptotic molecules Bax and Bak are directly activated by heat

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

p53 has a direct apoptogenic role at the mitochondria

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

PUMA, a novel proapoptotic gene, is induced by p53

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700380

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

25 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19380876

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200903134

1 reference

14 November 2017

1 reference

14 November 2017

1 reference

PMCID

2700380