The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues (Q28512628)

GOA release 2020-03-11

BCL2-antagonist/killer 1

1 reference

GOA release 2020-03-11

author name string

T. Lindsten

1

1 reference

25 January 2017

A. J. Ross

2

1 reference

25 January 2017

A. King

3

1 reference

25 January 2017

W. X. Zong

4

1 reference

25 January 2017

J. C. Rathmell

5

1 reference

25 January 2017

H. A. Shiels

6

1 reference

25 January 2017

E. Ulrich

7

1 reference

25 January 2017

K. G. Waymire

8

1 reference

25 January 2017

P. Mahar

9

1 reference

25 January 2017

K. Frauwirth

10

1 reference

25 January 2017

Y. Chen

11

1 reference

25 January 2017

M. Wei

12

1 reference

25 January 2017

V. M. Eng

13

1 reference

25 January 2017

D. M. Adelman

14

1 reference

25 January 2017

M. C. Simon

15

1 reference

25 January 2017

A. Ma

16

1 reference

25 January 2017

J. A. Golden

17

1 reference

25 January 2017

G. Evan

18

1 reference

25 January 2017

S. J. Korsmeyer

19

1 reference

25 January 2017

G. R. MacGregor

20

1 reference

25 January 2017

C. B. Thompson

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

21

1 reference

25 January 2017

1 December 2000

1 reference

25 January 2017

1 reference

25 January 2017

6

1 reference

25 January 2017

1389–1399

1 reference

25 January 2017

6

1 reference

25 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Generalized potential of adult neural stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

A new mouse insertional mutation that causes sensorineural deafness and vestibular defects

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Molecular characterization of mitochondrial apoptosis-inducing factor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bax directly induces release of cytochrome c from isolated mitochondria

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Apoptosis by death factor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

BAX is required for neuronal death after trophic factor deprivation and during development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Induction of apoptosis by the Bcl-2 homologue Bak

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

The Bcl-2 protein family: arbiters of cell survival

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

p53 is required for radiation-induced apoptosis in mouse thymocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Apoptotic pathways: paper wraps stone blunts scissors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Adult Apaf-1-deficient mice exhibit male infertility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Gene structure, cDNA sequence, and expression of murine Bak, a proapoptotic Bcl-2 family member

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Mouse vaginal opening is an apoptosis-dependent process which can be prevented by the overexpression of Bcl2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Progenitor cell proliferation outside the ventricular and subventricular zones during human brain development.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Modulation of cell death in yeast by the Bcl-2 family of proteins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Localization of bcl-2, bax, and bcl-x mRNAs in the developing inner ear of the mouse.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Thymocyte apoptosis induced by p53-dependent and independent pathways.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057227

Bik and Bak Induce Apoptosis Downstream of CrmA but Upstream of Inhibitor of Apoptosis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11163212

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell Death in Development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11163212

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11163212