Glutamate metabolism in the brain focusing on astrocytes. (Q43145476)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25236722%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Glutamate metabolism in the brain focusing on astrocytes (English)

1 reference

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16 February 2020

0 references

3

1 reference

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16 February 2020

Arne Schousboe

series ordinal

1

1 reference

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16 February 2020

Helle S. Waagepetersen

series ordinal

4

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16 February 2020

5

Mary C McKenna

1 reference

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16 February 2020

author name string

Susanna Scafidi

series ordinal

2

1 reference

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16 February 2020

publication date

1 January 2014

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16 February 2020

published in

Advances in neurobiology

1 reference

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16 February 2020

volume

11

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16 February 2020

page(s)

13-30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25236722%20AND%20SRC:MED&resulttype=core&format=json

Ontogenetic development of glutamate and GABA metabolizing enzymes in cultured cerebral cortex interneurons and in cerebral cortex in vivo.

16 February 2020

cites work

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Glutamate pays its own way in astrocytes

25 May 2018

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Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

25 May 2018

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Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA.

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Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures

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Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy.

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Glutamate dehydrogenase 1 and SIRT4 regulate glial development

25 May 2018

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Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes?

25 May 2018

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Primary cultures of astrocytes: their value in understanding astrocytes in health and disease.

25 May 2018

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The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology

25 May 2018

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Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria

25 May 2018

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Glutamate dehydrogenase in brain mitochondria: do lipid modifications and transient metabolon formation influence enzyme activity?

25 May 2018

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Astrocyte glutamine synthetase: importance in hyperammonemic syndromes and potential target for therapy

25 May 2018

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Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine

25 May 2018

1 reference

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Dietary branched chain amino acids ameliorate injury-induced cognitive impairment

25 May 2018

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Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)

25 May 2018

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The human GLUD2 glutamate dehydrogenase: localization and functional aspects

25 May 2018

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Uniquely hominid features of adult human astrocytes

25 May 2018

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Sirtuins--novel therapeutic targets to treat age-associated diseases

25 May 2018

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The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain

25 May 2018

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Metabolism of amino-acids: The synthesis of glutamine from glutamic acid and ammonia, and the enzymic hydrolysis of glutamine in animal tissues

25 May 2018

1 reference

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Cerebral metabolic disturbances in the brain during acute liver failure: from hyperammonemia to energy failure and proteolysis

25 May 2018

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Equilibria in transamination systems

25 May 2018

1 reference

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Kinetics and localization of brain phosphate activated glutaminase

25 May 2018

1 reference

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An energy budget for signaling in the grey matter of the brain

25 May 2018

1 reference

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Differential distribution of the enzymes glutamate dehydrogenase and aspartate aminotransferase in cortical synaptic mitochondria contributes to metabolic compartmentation in cortical synaptic terminals

25 May 2018

1 reference

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Clearance of glutamate inside the synapse and beyond

25 May 2018

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Regulation of gamma-aminobutyric acid synthesis in the brain

25 May 2018

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Uptake, release, and metabolism of alanine in neurons and astrocytes in primary cultures

25 May 2018

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Pyruvate carboxylase activity in primary cultures of astrocytes and neurons

25 May 2018

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An overview of glutamate as a neurotransmitter

25 May 2018

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A Simulation Study of the Metabolism and Compartmentation in Brain of Glutamate, Aspartate, the Krebs Cycle, and Related Metabolites

25 May 2018

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A simulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain

25 May 2018

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Regional and subcellular distribution of aminotransferases in rat brain

25 May 2018

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Purification and characterization of glutamate decarboxylase from mouse brain

25 May 2018

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The equilibrium constants of the glutamate dehydrogenase systems

25 May 2018

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Studies on the mechanism of inhibition of glutamine synthetase by methionine sulfoximine

25 May 2018

1 reference

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Immunohistochemical localization of glutamate decarboxylase in rat cerebellum

25 May 2018

1 reference

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Pyruvate carboxylase: an astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools

25 May 2018

1 reference

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Biochemistry and physiology of brain ammonia

25 May 2018

1 reference

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Glial glutamate dehydrogenase: ultrastructural localization and regional distribution in relation to the mitochondrial enzyme, cytochrome oxidase

25 May 2018

1 reference

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Effect of 8-bromo-cAMP and dexamethasone on glutamate metabolism in rat astrocytes

25 May 2018

1 reference

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Glutamate metabolism in rat cortical astrocyte cultures

25 May 2018

1 reference

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Phosphate activated glutaminase activity and glutamine uptake in primary cultures of astrocytes

25 May 2018

1 reference

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High Concentration of GABA and High Glutamate Decarboxylase Activity in Rat Pancreatic Islets and Human Insulinoma

25 May 2018

1 reference

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The metabolic fate of 13N-labeled ammonia in rat brain

25 May 2018

1 reference

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Fine structural localization of glutamine synthetase in astrocytes of rat brain

25 May 2018

1 reference

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Effect of aspartate on complexes between glutamate dehydrogenase and various aminotransferases

25 May 2018

1 reference

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Effects of adrenergic agents on intracellular Ca2+ homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxici

25 May 2018

1 reference

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Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

15 August 2018

1 reference

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Astrocytic complexity distinguishes the human brain

15 August 2018

1 reference

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Aspartate aminotransferase in synaptic and nonsynaptic mitochondria: differential effect of compounds that influence transient hetero-enzyme complex (metabolon) formation

15 August 2018

1 reference

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High-concentration rapid transients of glutamate mediate neural-glial communication via ectopic release.

15 August 2018

1 reference

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Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity.

15 August 2018

1 reference

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gamma-Aminobutyric acid in brain: its formation from glutamic acid.

15 August 2018

1 reference

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Studies on the Mechanism of Glutamine Synthesis; Isolation and Properties of the Enzyme from Sheep Brain*

15 August 2018

1 reference

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SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

15 August 2018

1 reference

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Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex

15 August 2018

1 reference

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Nitrogen shuttling between neurons and glial cells during glutamate synthesis

15 August 2018

1 reference

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Two isoforms of glutamate decarboxylase: why?

15 August 2018

1 reference

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[U-13C] aspartate metabolism in cultured cortical astrocytes and cerebellar granule neurons studied by NMR spectroscopy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667713

Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.

15 August 2018

1 reference

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Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667713

NMR spectroscopic studies of 13C acetate and 13C glucose metabolism in neocortical astrocytes: evidence for mitochondrial heterogeneity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667713

Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

15 August 2018

1 reference

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The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

31 March 2020

1 reference

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Metabolism of [U-13C]glutamate in astrocytes studied by 13C NMR spectroscopy: incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-08894-5_2

A possible role of alanine for ammonia transfer between astrocytes and glutamatergic neurons

31 March 2020

1 reference

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Metabolic fate of 14C-labeled glutamate in astrocytes in primary cultures

31 March 2020

1 reference

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Neuronal metabolism of branched-chain amino acids: flux through the aminotransferase pathway in synaptosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-08894-5_2

NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-08894-5_2

Phosphate-activated glutaminase in kidney and other tissues

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25236722

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/978-3-319-08894-5_2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25236722%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25236722%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

25236722

1 reference