Activating ROCK1 somatic mutations in human cancer (Q43169790)

15 November 2017

title

Activating ROCK1 somatic mutations in human cancer (English)

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15 November 2017

4

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15 November 2017

P A Lochhead

1

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15 November 2017

G Wickman

series ordinal

2

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15 November 2017

M Mezna

series ordinal

3

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15 November 2017

language of work or name

English

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publication date

8 February 2010

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15 November 2017

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15 November 2017

volume

29

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15 November 2017

issue

17

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15 November 2017

page(s)

2591-2598

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https://scigraph.springernature.com/pub.10.1038/onc.2010.3

15 November 2017

exact match

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cites work

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Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

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Patterns of somatic mutation in human cancer genomes

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

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An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

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The structure of dimeric ROCK I reveals the mechanism for ligand selectivity

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The rho/rho-kinase pathway is involved in the progression of testicular germ cell tumour.

21 January 2018

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Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma

21 January 2018

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Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

21 January 2018

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Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model

21 January 2018

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The actin cytoskeleton in cancer cell motility

21 January 2018

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RHO-GTPases and cancer

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Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner.

21 January 2018

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Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells

21 January 2018

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Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha

21 January 2018

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Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of rho kinases

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The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models

21 January 2018

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Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer

21 January 2018

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Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

31 March 2020

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Blockade of Rho/Rho-associated coiled coil-forming kinase signaling can prevent progression of hepatocellular carcinoma in matrix metalloproteinase-dependent manner

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.3

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Dimensions Publication ID

15 November 2017

1025790258

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