Incisor degeneration in rats induced by vascular endothelial growth factor/fibroblast growth factor receptor tyrosine kinase inhibition (Q43184381)

15 November 2017

Incisor degeneration in rats induced by vascular endothelial growth factor/fibroblast growth factor receptor tyrosine kinase inhibition (English)

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15 November 2017

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Anthony M Fletcher

1

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15 November 2017

Carla L Bregman

2

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15 November 2017

Jochen Woicke

3

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15 November 2017

Theodora W Salcedo

4

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15 November 2017

Robert H Zidell

5

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15 November 2017

Helen E Janke

6

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15 November 2017

Hengsheng Fang

7

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15 November 2017

William J Janusz

8

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15 November 2017

Gene E Schulze

9

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15 November 2017

Mark G Mense

10

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15 November 2017

language of work or name

English

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publication date

25 January 2010

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15 November 2017

Toxicologic Pathology

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15 November 2017

38

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15 November 2017

2

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15 November 2017

267-279

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Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

15 November 2017

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Expression of protein kinases C betaI, betaII, and VEGF during the differentiation of enamel epithelium in tooth development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Developmental dental toxicity of dioxin and related compounds--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Role of tyrosine kinase inhibitors in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Regulation of vascular development by fibroblast growth factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Cartilage dysplasia and tissue mineralization in the rat following administration of a FGF receptor tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Angiogenesis in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular endothelial growth factor (VEGF) in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factors and their receptors in urological cancers: basic research and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

VEGF: an essential mediator of both angiogenesis and endochondral ossification

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vasculogenesis and angiogenesis in the early human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Angiogenesis: update 2005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Cellular signaling by fibroblast growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Molecular and biological properties of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The biology of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The biology of VEGF and its receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Innate immunity and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Regulation of the ovarian follicular vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Recent advances in endometrial angiogenesis research

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Pegaptanib for neovascular age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

A role for VEGF as a negative regulator of pericyte function and vessel maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factor signaling in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Review of the effects of anti-angiogenic compounds on the epiphyseal growth plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular endothelial growth factor: biology and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Spectrum of activity and mechanism of action of VEGF/PDGF inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Evolution of the Fgf and Fgfr gene families

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Histopathological study on the PTHrP-induced incisor lesions in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

VEGF/VEGFR signalling as a target for inhibiting angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Response of the incisor tooth to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a dioxin-resistant and a dioxin-sensitive rat strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Review article. The rat incisor in toxicologic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Hexachlorobenzene-induced incisor degeneration in Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Dental dysplasia in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Immunolocalization of fibroblast growth factor-2 (FGF-2) in the developing root and supporting structures of the murine tooth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Small-molecule inhibitors of fibroblast growth factor receptor (FGFR) tyrosine kinases (TK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factors and their inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Structural features of forming and developing blood capillaries of the enamel organ of rat molar tooth germs observed by light and electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Increased expression of fibroblast growth factor 8 in human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Mouse models of abnormal skeletal development and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Normal and abnormal dental development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The potential role of vascular endothelial growth factor (VEGF) in cartilage: how the angiogenic factor could be involved in the pathogenesis of osteoarthritis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

VEGF function in vascular pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

FGF signalling in craniofacial development and developmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular endothelial growth factor family of ligands and receptors: review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Nonclinical safety evaluation of sunitinib: a potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Angiogenesis in the female reproductive organs: pathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Angiogenic growth factors in human dentine matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Biology of vascular endothelial growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenesis strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Evolution of bevacizumab-based therapy in the management of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Morphological classification of dental lesions induced by various antitumor drugs in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Role of the microenvironment in tumor growth and in refractoriness/resistance to anti-angiogenic therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Epithelial fibroblast growth factor receptor 1 regulates enamel formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Molecular regulation of tooth development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Signalling networks regulating dental development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Angiogenesis in implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Fgf-2 regulates enamel and dentine formation in mouse tooth germ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The importance of signal pathway modulation in all aspects of tooth development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebellar ataxia [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

An integrated gene regulatory network controls stem cell proliferation in teeth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

FGFR activation in skeletal disorders: too much of a good thing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Craniosynostosis: genes and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Cellular and molecular basis of tooth eruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Perspective. Osteoclastogenesis and growth plate chondrocyte differentiation: emergence of convergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357950

21 January 2018

Identifiers

DOI

10.1177/0192623309357950

1 reference

15 November 2017

1 reference