Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. (Q43188994)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19127257%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53 (English)

1 reference

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19 January 2020

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2

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19 January 2020

Christopher W. Schmidt

6

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19 January 2020

author name string

S C Naumann

1

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19 January 2020

E Jöst

3

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19 January 2020

C Belohlavek

4

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19 January 2020

V Lennerz

5

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19 January 2020

M Christmann

7

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19 January 2020

B Kaina

8

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19 January 2020

language of work or name

English

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publication date

6 January 2009

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British Journal of Cancer

19 January 2020

published in

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19 January 2020

volume

100

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19 January 2020

issue

2

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19 January 2020

page(s)

322-333

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Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling

19 January 2020

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Microarray expression profiling in melanoma reveals a BRAF mutation signature.

25 May 2018

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Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related

25 May 2018

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O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma

25 May 2018

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Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.

25 May 2018

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25 May 2018

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Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT.

25 May 2018

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25 May 2018

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Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma

25 May 2018

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Human melanoma cell line UV responses show independency of p53 function.

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

25 May 2018

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O6-methylguanine-DNA methyltransferase activity in human tumors

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs

25 May 2018

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Phase II study of extended-dose temozolomide in patients with melanoma

15 August 2018

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Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases

15 August 2018

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15 August 2018

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Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

15 August 2018

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DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system

15 August 2018

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Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.

15 August 2018

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The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.

15 August 2018

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Analysis of O(6)-methylguanine-DNA methyltransferase in melanoma tumours in patients treated with dacarbazine-based chemotherapy

15 August 2018

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Immunohistochemical analysis of DNA mismatch repair protein and O6-methylguanine-DNA methyltransferase in melanoma metastases in relation to clinical response to DTIC-based chemotherapy

15 August 2018

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Expression of DNA repair proteins hMSH2, hMSH6, hMLH1, O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in melanoma cells with acquired drug resistance.

15 August 2018

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Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting.

15 August 2018

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15 August 2018

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Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl]ethane in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.

15 August 2018

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15 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604856

Formation of DNA interstrand cross-links by the novel chloroethylating agent 2-chloroethyl(methylsulfonyl)methanesulfonate: suppression by O6-alkylguanine-DNA alkyltransferase purified from human leukemic lymphoblasts

21 January 2018

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12 December 2020

Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models

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O6-alkylguanine DNA lesions trigger apoptosis

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12 December 2020

Inhibition of RNA polymerase II as a trigger for the p53 response

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12 December 2020

Altered expression of the DNA mismatch repair proteins hMLH1 and hMSH2 in cutaneous dysplastic nevi and malignant melanoma

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Immunocytochemical detection of hMSH2 and hMLH1 expression in oral melanoma

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Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6604856

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19127257%20AND%20SRC:MED&resulttype=core&format=json

release_7tr2khqrdfekhptu65moeag6km

19 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7tr2khqrdfekhptu65moeag6km

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19127257%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

19127257

1 reference