Plumbagin shows anticancer activity in human osteosarcoma (MG-63) cells via the inhibition of S-Phase checkpoints and down-regulation of c-myc (Q43209700)

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scientific article published on 15 August 2015

Language	Label	Description	Also known as
English	Plumbagin shows anticancer activity in human osteosarcoma (MG-63) cells via the inhibition of S-Phase checkpoints and down-regulation of c-myc	scientific article published on 15 August 2015

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Plumbagin shows anticancer activity in human osteosarcoma (MG-63) cells via the inhibition of S-Phase checkpoints and down-regulation of c-myc (English)

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

author name string

Chao-Hua Yan

1

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Feng Li

2

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Yuan-Chen Ma

3

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

publication date

15 August 2015

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

International Journal of Clinical and Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

8

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

8

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

14432-14439

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Inhibitory effects of tamoxifen and doxorubicin, alone and in combination, on the proliferation of the MG63 human osteosarcoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

25 May 2018

Microwave-assisted synthesis of arene ruthenium(II) complexes that induce S-phase arrest in cancer cells by DNA damage-mediated p53 phosphorylation

1 reference

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25 May 2018

Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.

1 reference

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25 May 2018

The natural anticancer agent plumbagin induces potent cytotoxicity in MCF-7 human breast cancer cells by inhibiting a PI-5 kinase for ROS generation

1 reference

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25 May 2018

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

1 reference

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25 May 2018

DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells

1 reference

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25 May 2018

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

1 reference

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25 May 2018

C-MYC alterations and association with patient outcome in early-stage HER2-positive breast cancer from the north central cancer treatment group N9831 adjuvant trastuzumab trial.

1 reference

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25 May 2018

An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction

1 reference

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Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines

1 reference

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25 May 2018

Anticancer mechanism of plumbagin, a natural compound, on non-small cell lung cancer cells.

1 reference

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25 May 2018

Non-transcriptional control of DNA replication by c-Myc

1 reference

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25 May 2018

Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells

1 reference

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25 May 2018

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

25 May 2018

Recombinant antisense C-myc adenovirus increase in vitro sensitivity of osteosarcoma MG-63 cells to cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

25 May 2018

Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

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25 May 2018

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

25 May 2018

You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

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25 May 2018

Phytochemicals as cell cycle modulators--a less toxic approach in halting human cancers.

1 reference

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25 May 2018

Progress toward the development of agents to modulate the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

25 May 2018

The biochemistry of apoptosis

1 reference

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25 May 2018

gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.

1 reference

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25 May 2018

Osteosarcoma in 2 Very Young Children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

25 May 2018

Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

15 August 2018

c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

15 August 2018

Synthesis of plumbagin derivatives and their inhibitory activities against Ehrlich ascites carcinoma in vivo and Leishmania donovani Promastigotes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613116

15 August 2018

Adolescent bone cancer: is the growth spurt implicated?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plumbagin: A study of its anticancer, antibacterial & antifungal properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary osteogenic sarcoma of the calvaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[On the relationship between the rate of skeletal growth and the development of primary osteogenic sarcoma]

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Growth of bones and osteogenic sarcoma]

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of plumbagin on the radiation induced cytogenetic and cell cycle changes in mouse Ehrlich ascites carcinoma in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on osteogenous-osteogenetic sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteogenic sarcoma of bones and soft tissues in older persons. A clinicopathologic analysis of 117 patients older than 60 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/26550431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

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