Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death (Q43271690)

18 November 2017

Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death (English)

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18 November 2017

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18 November 2017

E Lafont

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author name string

D Milhas

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18 November 2017

S Carpentier

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18 November 2017

V Garcia

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Z-X Jin

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H Umehara

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T Okazaki

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K Schulze-Osthoff

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T Levade

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H Benoist

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18 November 2017

25 September 2009

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Cell Death & Differentiation

18 November 2017

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17

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4

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18 November 2017

642-654

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https://scigraph.springernature.com/pub.10.1038/cdd.2009.130

18 November 2017

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cites work

Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

The role of receptor internalization in CD95 signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Sphingolipids as modulators of cancer cell death: potential therapeutic targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Glucosylceramide synthase does not attenuate the ceramide pool accumulating during apoptosis induced by CD95 or anti-cancer regimens

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Identification of a family of animal sphingomyelin synthases

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.130

Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Differential regulation of sphingomyelin synthesis and catabolism in oligodendrocytes and neurons

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Molecular machinery for non-vesicular trafficking of ceramide

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Role of membrane sphingomyelin and ceramide in platform formation for Fas-mediated apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Golgi fragmentation during Fas-mediated apoptosis is associated with the rapid loss of GM130.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Raft ceramide in molecular medicine

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Sphingomyelin synthases regulate production of diacylglycerol at the Golgi

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Ceramide: second messenger or modulator of membrane structure and dynamics?

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Death receptor ligation triggers membrane scrambling between Golgi and mitochondria.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Golgi fragmentation is associated with ceramide-induced cellular effects.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Lipids and the exocytotic machinery of eukaryotic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.130

Changes in bioactive lipids, alkylacylglycerol and ceramide, occur in HIV-infected cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Synthesis and biological activity of a novel inhibitor of dihydroceramide desaturase

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

CD40 signals apoptosis through FAN-regulated activation of the sphingomyelin-ceramide pathway.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

FLICE Induced Apoptosis in a Cell-free System

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

7 January 2021

Unique and overlapping substrate specificities of caspase-8 and caspase-10.

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

7 January 2021

Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

7 January 2021

Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

7 January 2021

Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

7 January 2021

Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase

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https://api.crossref.org/works/10.1038%2FCDD.2009.130

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.130

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Dimensions Publication ID

18 November 2017

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