UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal). (Q43284930)

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scientific article published in January 2009

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English	UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal).	scientific article published in January 2009

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scholarly article

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6 February 2020

UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal) (English)

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6 February 2020

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Maria José Brilhante

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6 February 2020

Cristina Ballart

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6 February 2020

Luisa Mota-Vieira

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6 February 2020

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Paula R Pacheco

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6 February 2020

Francesc Sigalat

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6 February 2020

Helena Polena

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6 February 2020

Rita Cabral

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6 February 2020

Claudia C Branco

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1 January 2009

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6 February 2020

Molecular Diagnosis and Therapy

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6 February 2020

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6 February 2020

4

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6 February 2020

261-268

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6 February 2020

https://scigraph.springernature.com/pub.10.1007/bf03256331

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Pharmacogenomics: unlocking the human genome for better drug therapy

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Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.

1 reference

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The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

1 reference

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UDP-glucuronosyltransferase activity in human liver and colon

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Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine

1 reference

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21 January 2018

Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity

1 reference

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Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

1 reference

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21 January 2018

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

1 reference

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HLA class I and II polymorphisms in Azores show different settlements in Oriental and Central islands.

1 reference

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Azores Islands: genetic origin, gene flow and diversity pattern.

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Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

1 reference

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Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications

1 reference

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Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene

1 reference

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21 January 2018

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk

1 reference

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21 January 2018

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

1 reference

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21 January 2018

Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03256331

21 January 2018

Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer

1 reference

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21 January 2018

"Irinogenetics" and UGT1A: from genotypes to haplotypes

1 reference

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21 January 2018

Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype

1 reference

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21 January 2018

Frequent co-occurrence of the TATA box mutation associated with Gilbert’s syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians

1 reference

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21 January 2018

Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

1 reference

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21 January 2018

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus

1 reference

https://api.crossref.org/works/10.1007%2FBF03256331

21 January 2018

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk

1 reference

https://api.crossref.org/works/10.1007%2FBF03256331

21 January 2018

UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer

1 reference

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21 January 2018

UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma in japanese patients with hepatitis C virus infection

1 reference

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21 January 2018

Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes

1 reference

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21 January 2018

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

1 reference

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21 January 2018

The Y-chromosomal Heritage of the Azores Islands Population

1 reference

https://api.crossref.org/works/10.1007%2FBF03256331

21 January 2018

UGT1A polymorphisms in a Swedish cohort and a human diversity panel, and the relation to bilirubin plasma levels in males and females.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

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The Y-chromosomal heritage of the Azores Islands population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage disequilibrium of UGT1A1 *6 and UGT1A1 *28 in relation to UGT1A6 and UGT1A7 polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research

1 reference

https://pubmed.ncbi.nlm.nih.gov/19712005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03256331

1 reference

Europe PubMed Central

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6 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19712005%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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