Neoplastic and non-neoplastic changes in F-344 rats treated with Naveglitazar, a gamma-dominant PPAR alpha/gamma agonist (Q43287595)

18 November 2017

Neoplastic and non-neoplastic changes in F-344 rats treated with Naveglitazar, a gamma-dominant PPAR alpha/gamma agonist (English)

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18 November 2017

Gerald G Long

1

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18 November 2017

Vincent L Reynolds

series ordinal

2

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18 November 2017

L Wayne Dochterman

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3

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18 November 2017

Thomas E Ryan

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4

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18 November 2017

language of work or name

English

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publication date

21 August 2009

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18 November 2017

Toxicologic Pathology

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18 November 2017

37

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18 November 2017

6

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18 November 2017

741-753

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An antidiabetic thiazolidinedione induces eccentric cardiac hypertrophy by cardiac volume overload in rats

18 November 2017

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

The mechanisms of action of PPARs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Effects of stones and other physical factors on the induction of rodent bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

S-100 antigen labels neoplastic cells in liposarcoma and cartilaginous tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Urinary tract calculi and thresholds in carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Effects of PPARgamma and combined agonists on the urinary tract of rats and other species

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Urothelial carcinogenesis in the urinary bladder of male rats treated with muraglitazar, a PPAR alpha/gamma agonist: Evidence for urolithiasis as the inciting event in the mode of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

New Tables for Multiple Comparisons with a Control

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Neoplastic and nonneoplastic lesions in aging F344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Histopathology of hemangiosarcomas in mice and hamsters and liposarcomas/fibrosarcomas in rats associated with PPAR agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Rodent carcinogenicity with the thiazolidinedione antidiabetic agent troglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

PPARgamma ligands suppress proliferation of human urothelial basal cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

PPARalpha agonist-induced rodent tumors: modes of action and human relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Overall false positive rates in tests for linear trend in tumor incidence in animal carcinogenicity studies of new drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Urothelial carcinogenesis in the urinary bladder of rats treated with naveglitazar, a gamma-dominant PPAR alpha/gamma agonist: lack of evidence for urolithiasis as an inciting event

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Terminal differentiation of human breast cancer through PPAR gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Peroxisome proliferator-activated receptor γ (PPARγ) ligands as bifunctional regulators of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Therapeutic potential of thiazolidinediones as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Molecular regulation of adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Activators of the nuclear receptor PPARgamma enhance colon polyp formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

PPAR gamma signaling exacerbates mammary gland tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Rodent carcinogenicity profile of the antidiabetic dual PPAR alpha and gamma agonist muraglitazar.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

A FORTRAN program to perform the nonparametric Terpstra-Jonckheere test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Trend and homogeneity analyses of proportions and life table data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Activation of peroxisome proliferator-activated receptor-gamma reverses squamous metaplasia and induces transitional differentiation in normal human urothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Nonclinical safety evaluation of muraglitazar, a novel PPARalpha/gamma agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

Differential Regulation of Vascular Endothelial Growth Factor Expression by Peroxisome Proliferator-activated Receptors in Bladder Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623309343775

21 January 2018

Identifiers

DOI

10.1177/0192623309343775

1 reference

18 November 2017

1 reference