The role of stem cell factor and c-KIT in keloid pathogenesis: do tyrosine kinase inhibitors have a potential therapeutic role? (Q43436232)

23 November 2017

The role of stem cell factor and c-KIT in keloid pathogenesis: do tyrosine kinase inhibitors have a potential therapeutic role? (English)

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23 November 2017

6

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23 November 2017

A Mukhopadhyay

1

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23 November 2017

D V Do

2

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23 November 2017

C T Ong

3

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23 November 2017

Y T Khoo

4

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23 November 2017

J Masilamani

5

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23 November 2017

A S Vincent

7

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23 November 2017

P K Wong

8

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23 November 2017

C P Lim

9

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23 November 2017

X Cao

10

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23 November 2017

I J Lim

11

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23 November 2017

T T Phan

12

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23 November 2017

language of work or name

English

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publication date

22 December 2010

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British Journal of Dermatology

23 November 2017

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23 November 2017

164

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23 November 2017

2

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23 November 2017

372-386

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Excessive scarring as a consequence of healing

23 November 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

The molecular basis of keloid and hypertrophic scar formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

On the nature of hypertrophic scars and keloids: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

The role of the activin system in keloid pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Overexpression of insulin-like growth factor-1 (IGF-I) receptor and the invasiveness of cultured keloid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

The biology of stem cell factor and its receptor C-kit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Identification of a ligand for the c-kit proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Specificity of a mouse monoclonal antibody raised against acute myeloid leukaemia cells for mast cells in human mucosal and connective tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

c-kit protein, a transmembrane kinase: identification in tissues and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Human mast cells stimulate fibroblast proliferation, collagen synthesis and lattice contraction: a direct role for mast cells in skin fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Stem cell factor and crescentic glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

The transcriptional program in the response of human fibroblasts to serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Sulfite-mediated oxidative stress in kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

c-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Investigation of the influence of keloid-derived keratinocytes on fibroblast growth and proliferation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in a keloidlike manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Catalytic properties of ADAM19

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Catalytic activity of human ADAM33

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Inhibition by glucocorticoids of the interleukin-1beta-enhanced expression of the mast cell growth factor SCF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Stem cell factor restores hepatocyte proliferation in IL-6 knockout mice following 70% hepatectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Soluble c‐kit molecule in serum from healthy individuals and patients with haemopoietic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Targeting c-Kit mutations: basic science to novel therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Imatinib as a novel antifibrotic agent in bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Hepatoma-derived growth factor is involved in lung remodeling by stimulating epithelial growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Role of Fibroblast Growth Factor Type 1 and 2 in Carbon Tetrachloride-Induced Hepatic Injury and Fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2010.10035.X

10.1111/J.1365-2133.2010.10035.X

21 January 2018

Identifiers

DOI

1 reference

23 November 2017

1 reference