By-products of immunoglobulin somatic hypermutation (Q43442944)

23 November 2017

By-products of immunoglobulin somatic hypermutation (English)

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23 November 2017

1

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23 November 2017

Michael S Neuberger

2

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23 November 2017

1 September 2003

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Genes, Chromosomes and Cancer

23 November 2017

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23 November 2017

38

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23 November 2017

1

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23 November 2017

32-39

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The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line

23 November 2017

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7 January 2021

Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

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7 January 2021

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

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7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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7 January 2021

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

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7 January 2021

Somatic hypermutation in normal and transformed human B cells.

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7 January 2021

Mechanisms of chromosomal translocations in B cell lymphomas

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7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

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7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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7 January 2021

The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially

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7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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7 January 2021

The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance

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7 January 2021

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

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7 January 2021

Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes

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7 January 2021

Activation of a translocated c-myc gene: role of structural alterations in the upstream region

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7 January 2021

Identifiers

DOI

10.1002/GCC.10241

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23 November 2017

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PubMed ID

12874784