Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain (Q43518984)

24 November 2017

Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain (English)

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24 November 2017

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24 November 2017

Andisheh Eslamboli

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24 November 2017

Nicholas Muzyczka

5

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24 November 2017

Ronald J Mandel

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24 November 2017

Harry Baker

7

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24 November 2017

Rosalind M Ridley

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24 November 2017

Deniz Kirik

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24 November 2017

language of work or name

English

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publication date

15 February 2007

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24 November 2017

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24 November 2017

130

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24 November 2017

Pt 3

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24 November 2017

799-815

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Behavioural analysis of unilateral monoamine depletion in the marmoset.

24 November 2017

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

The biochemistry of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Sensorimotor deficits in a unilateral intrastriatal 6-OHDA partial lesion model of Parkinson's disease in marmoset monkeys.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

A Drosophila model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Alpha-synuclein and transgenic mouse models

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Synucleinopathies: clinical and pathological implications

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Widespread occurrence of argyrophilic glial inclusions in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Contralesional neglect in monkeys with small unilateral parietal cortical ablations.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Dissociation of hemi-spatial and hemi-motor impairments in a unilateral primate model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

The role of alpha-synuclein in the pathogenesis of multiple system atrophy

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

CMV-beta-actin promoter directs higher expression from an adeno-associated viral vector in the liver than the cytomegalovirus or elongation factor 1 alpha promoter and results in therapeutic levels of human factor X in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWL382

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWL382

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24 November 2017

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