Up-regulation of Ras/Raf/ERK1/2 signaling impairs cultured neuronal cell migration, neurogenesis, synapse formation, and dendritic spine development (Q43538904)

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scientific article published on 5 May 2012

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English	Up-regulation of Ras/Raf/ERK1/2 signaling impairs cultured neuronal cell migration, neurogenesis, synapse formation, and dendritic spine development	scientific article published on 5 May 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 November 2017

Up-regulation of Ras/Raf/ERK1/2 signaling impairs cultured neuronal cell migration, neurogenesis, synapse formation, and dendritic spine development (English)

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Europe PubMed Central

PubMed publication ID

24 November 2017

dendritic spine

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based on heuristic

inferred from title

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based on heuristic

inferred from title

5

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24 November 2017

author name string

Kun Yang

1

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24 November 2017

Fujiang Cao

2

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Europe PubMed Central

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24 November 2017

Ashfaq M Sheikh

3

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Europe PubMed Central

PubMed publication ID

24 November 2017

Mazhar Malik

4

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Europe PubMed Central

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24 November 2017

Hongen Wei

6

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PubMed publication ID

24 November 2017

W Ted Brown

7

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24 November 2017

Xiaohong Li

8

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24 November 2017

publication date

5 May 2012

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24 November 2017

Brain Structure and Function

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24 November 2017

218

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24 November 2017

3

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24 November 2017

669-682

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Europe PubMed Central

PubMed publication ID

24 November 2017

Levels of Bcl-2 and P53 are altered in superior frontal and cerebellar cortices of autistic subjects

1 reference

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FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies

1 reference

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Fragile X syndrome and autism at the intersection of genetic and neural networks

1 reference

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Balancing structure and function at hippocampal dendritic spines

1 reference

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Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

1 reference

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Development and Regulation of Dendritic Spine Synapses

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A genetic variant that disrupts MET transcription is associated with autism

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Epilepsy in autism spectrum disorders

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Role of extracellular signal regulated kinase 5 in neuronal survival.

1 reference

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PTEN and the PI3-kinase pathway in cancer

1 reference

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Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades

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Mitogen-activated protein kinase/extracellular regulated kinase signalling and memory stabilization: a review

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Regulatory mechanisms of AMPA receptors in synaptic plasticity

1 reference

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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

1 reference

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Altered levels of Bcl2 and p53 proteins in parietal cortex reflect deranged apoptotic regulation in autism.

1 reference

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21 January 2018

Reduction in anti-apoptotic protein Bcl-2 in autistic cerebellum.

1 reference

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Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

PTEN mutation in a family with Cowden syndrome and autism

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Synaptic plasticity, AMPA-R trafficking, and Ras-MAPK signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Autism profiles of males with fragile X syndrome

1 reference

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21 January 2018

Actin in dendritic spines: connecting dynamics to function

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Diacylglycerol kinase beta promotes dendritic outgrowth and spine maturation in developing hippocampal neurons

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Structural dynamics of dendritic spines in memory and cognition

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Activity patterns govern synapse-specific AMPA receptor trafficking between deliverable and synaptic pools

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Disruption of neurexin 1 associated with autism spectrum disorder

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Recurrent 16p11.2 microdeletions in autism

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Pten regulates neuronal arborization and social interaction in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Immature and mature cortical neurons engage different apoptotic mechanisms involving caspase-3 and the mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders

1 reference

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Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis

1 reference

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NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf/MEK/MAPK cascade

1 reference

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Expression of inflammatory cytokines, Bcl2 and cathepsin D are altered in lymphoblasts of autistic subjects.

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

AKT/PKB signaling: navigating downstream

1 reference

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21 January 2018

Structural basis of long-term potentiation in single dendritic spines

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Integrating signals from RTKs to ERK/MAPK.

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Contribution of SHANK3 mutations to autism spectrum disorder

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

MAPK signal specificity: the right place at the right time

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Structure and function of dendritic spines

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

AMPA receptors are exocytosed in stimulated spines and adjacent dendrites in a Ras-ERK-dependent manner during long-term potentiation

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

State-dependent Ras signaling and AMPA receptor trafficking

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

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Control of axonal branching and synapse formation by focal adhesion kinase

1 reference

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Model of autism: increased ratio of excitation/inhibition in key neural systems

1 reference

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21 January 2018

The ERK cascade: a prototype of MAPK signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

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The endocannabinoid anandamide inhibits neuronal progenitor cell differentiation through attenuation of the Rap1/B-Raf/ERK pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

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Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation

1 reference

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Role of Akt and ERK signaling in the neurogenesis following brain ischemia

1 reference

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Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

1 reference

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21 January 2018

Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures

1 reference

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A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death

1 reference

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Mapping autism risk loci using genetic linkage and chromosomal rearrangements

1 reference

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21 January 2018

Molecular mechanisms of dendritic spine morphogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Activity of the AMPA receptor regulates drebrin stabilization in dendritic spine morphogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

MAPK cascade signalling and synaptic plasticity

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Neuronal migration mechanisms in development and disease

1 reference

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21 January 2018

Synapse pathology in psychiatric and neurologic disease

1 reference

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21 January 2018

Activation of extracellular signal-regulated kinase 5 may play a neuroprotective role in hippocampal CA3/DG region after cerebral ischemia

1 reference

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21 January 2018

Effects of FAK ablation on cerebellar foliation, Bergmann glia positioning and climbing fiber territory on Purkinje cells

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Association between microdeletion and microduplication at 16p11.2 and autism

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Upregulation of Ras/Raf/ERK1/2 signaling and ERK5 in the brain of autistic subjects.

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Morphological changes in dendritic spines associated with long-term synaptic plasticity

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Acute versus chronic NMDA receptor blockade and synaptic AMPA receptor delivery

1 reference

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Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?

1 reference

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21 January 2018

Association of upregulated Ras/Raf/ERK1/2 signaling with autism.

1 reference

https://api.crossref.org/works/10.1007%2FS00429-012-0420-7

21 January 2018

Identifiers

10.1007/S00429-012-0420-7

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

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