3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3). (Q43552091)

24 November 2017

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3). (English)

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24 November 2017

Smith DG

1

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24 November 2017

Buffet M

2

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24 November 2017

Fenwick AE

3

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24 November 2017

Haigh D

4

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24 November 2017

Ife RJ

5

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24 November 2017

Saunders M

6

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24 November 2017

Slingsby BP

7

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24 November 2017

Stacey R

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24 November 2017

Ward RW

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24 November 2017

language of work or name

English

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publication date

1 March 2001

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Bioorganic & Medicinal Chemistry Letters

24 November 2017

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24 November 2017

11

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24 November 2017

5

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24 November 2017

635-639

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Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle

24 November 2017

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Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism

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Control of glycogen synthase by hierarchal protein phosphorylation

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Multiple mechanisms for the phosphorylation of C-terminal regulatory sites in rabbit muscle glycogen synthase expressed in COS cells

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Mechanisms of multisite phosphorylation and inactivation of rabbit muscle glycogen synthase

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Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells

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Pathogenesis of NIDDM. A balanced overview

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Intracellular glucose oxidation and glycogen synthase activity are reduced in non-insulin-dependent (type II) diabetes independent of impaired glucose uptake

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Insulin resistance in skeletal muscles in patients with NIDDM.

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Correlation between muscle glycogen synthase activity and in vivo insulin action in man.

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Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

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Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons.

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Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides

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The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase.

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity

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Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives

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Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

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Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

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Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

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Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

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Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

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Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

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Identifiers

DOI

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24 November 2017

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