Activated JNK phosphorylates the c-terminal domain of MLK2 that is required for MLK2-induced apoptosis (Q43559392)

24 November 2017

Activated JNK phosphorylates the c-terminal domain of MLK2 that is required for MLK2-induced apoptosis (English)

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24 November 2017

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Phelan DR

1

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24 November 2017

Price G

series ordinal

2

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24 November 2017

Liu YF

series ordinal

3

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24 November 2017

Dorow DS

series ordinal

4

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24 November 2017

language of work or name

English

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publication date

12 January 2001

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

14

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24 November 2017

10801-10810

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Insulin signal transduction through protein kinase cascades.

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Mitogen-activated protein kinase cascades as regulators of stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Raf-1 activates MAP kinase-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Feedback regulation of map kinase signal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/mixed lineage kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Dual leucine zipper-bearing kinase (DLK) activates p46SAPK and p38mapk but not ERK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Huntington's disease: translating a CAG repeat into a pathogenic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Measurement of protein using bicinchoninic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

IL-2 deprivation triggers apoptosis which is mediated by c-Jun N-terminal kinase 1 activation and prevented by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

A cytoplasmic inhibitor of the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

A mammalian scaffold complex that selectively mediates MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

The JIP group of mitogen-activated protein kinase scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

14-3-3 proteins block apoptosis and differentially regulate MAPK cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

The riddle of MAP kinase signaling specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008237200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008237200

1 reference

24 November 2017

1 reference