Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome (Q43559407)

24 November 2017

Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome (English)

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24 November 2017

Seebohm G

1

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24 November 2017

Scherer CR

series ordinal

2

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24 November 2017

Busch AE

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3

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24 November 2017

Lerche C

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4

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24 November 2017

language of work or name

English

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publication date

17 January 2001

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

17

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24 November 2017

13600-13605

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Inactivation of the sodium channel. II. Gating current experiments

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Biophysical and molecular mechanisms of Shaker potassium channel inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Dynamic rearrangement of the outer mouth of a K+ channel during gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Human sodium channel myotonia: slowed channel inactivation due to substitutions for a glycine within the III-IV linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Molecular mechanism for an inherited cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

A potassium channel mutation in neonatal human epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Cloning of a membrane protein that induces a slow voltage-gated potassium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Dominant-negative KvLQT1 mutations underlie the LQT1 form of long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Pathophysiological mechanisms of dominant and recessive KVLQT1 K+ channel mutations found in inherited cardiac arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

KCNE1 mutations cause jervell and Lange-Nielsen syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Activation and inactivation of homomeric KvLQT1 potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Long QT syndrome-associated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Molecular mechanism and functional significance of the MinK control of the KvLQT1 channel activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

The conduction pore of a cardiac potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

The inward rectification mechanism of the HERG cardiac potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

A new wave for heart rhythms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008373200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008373200

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1 reference