Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism. (Q43559492)

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English	Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism.	scientific article

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6 November 2019

Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism (English)

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6 November 2019

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6 November 2019

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N Cheng

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6 November 2019

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2 February 2001

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6 November 2019

Journal of Biological Chemistry

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6 November 2019

276

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6 November 2019

13771-13777

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6 November 2019

17

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6 November 2019

Mechanisms of angiogenesis

1 reference

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Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development

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Growth factor signaling pathways in vascular development

1 reference

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Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity

1 reference

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Ephrins and their receptors: a repulsive topic?

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Tyrosine phosphorylation of transmembrane ligands for Eph receptors

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Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

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21 January 2018

Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion

1 reference

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21 January 2018

Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

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Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

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Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

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Ephrin-A1 is expressed at sites of vascular development in the mouse

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21 January 2018

Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis

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A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

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Spontaneous transformation and immortalization of human endothelial cells

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Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

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Tumor necrosis factor receptor and Fas signaling mechanisms.

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Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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Differential serine phosphorylation regulates IkappaB-alpha inactivation.

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase

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Activation of Jun N-terminal Kinase/Stress-activated Protein Kinase Pathway by Tumor Necrosis Factor α Leads to Intercellular Adhesion Molecule-1 Expression

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Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

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Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-associated factor 2 (TRAF2) and nuclear factor kappaB pathways

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Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

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TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.

1 reference

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From receptors to stress-activated MAP kinases

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p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

1 reference

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Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1.

1 reference

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Homeobox B3 promotes capillary morphogenesis and angiogenesis

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Inhibition of Tumor Necrosis Factor Signal Transduction in Endothelial Cells by Dimethylaminopurine

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Identifiers

10.1074/JBC.M009147200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278471%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278471%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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