NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions (Q43559619)

24 November 2017

NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions (English)

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24 November 2017

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Stoletov KV

1

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24 November 2017

Ratcliffe KE

series ordinal

2

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24 November 2017

Spring SC

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3

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24 November 2017

Terman BI

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4

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24 November 2017

language of work or name

English

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publication date

8 March 2001

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

25

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24 November 2017

22748-22755

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

24 November 2017

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Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue

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Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization

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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

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The hemostatic system as a regulator of angiogenesis

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Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

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Vascular endothelial growth factor is a secreted angiogenic mitogen

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The biology of vascular endothelial growth factor

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

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A little VEGF goes a long way. Therapeutic angiogenesis by direct injection of vascular endothelial growth factor-encoding plasmid DNA.

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

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Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: a role of VEGF and possible treatment for SRN in age-related macular degeneration

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Cell adhesion: the molecular basis of tissue architecture and morphogenesis

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Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

21 January 2018

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 January 2018

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Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins.

21 January 2018

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Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins

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Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

21 January 2018

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

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A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

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Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

21 January 2018

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Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

21 January 2018

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Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

21 January 2018

1 reference

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Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

21 January 2018

1 reference

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Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

21 January 2018

1 reference

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

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FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

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Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

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Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization

21 January 2018

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The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events

21 January 2018

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Biological activity and phosphorylation sites of the bacterially expressed cytosolic domain of the KDR VEGF-receptor

21 January 2018

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VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor

21 January 2018

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21 January 2018

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

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Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

21 January 2018

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Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

1 reference

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Kinase insert domain receptor (KDR) extracellular immunoglobulin-like domains 4-7 contain structural features that block receptor dimerization and vascular endothelial growth factor-induced signaling

21 January 2018

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Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor

21 January 2018

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Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck

21 January 2018

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Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules

21 January 2018

1 reference

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Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

21 January 2018

1 reference

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The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

21 January 2018

1 reference

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Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

21 January 2018

1 reference

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Structural requirements for PAK activation by Rac GTPases

21 January 2018

1 reference

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Mechanism of activation of Pak1 kinase by membrane localization

21 January 2018

1 reference

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A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.

21 January 2018

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

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21 January 2018

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Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation

21 January 2018

1 reference

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

1 reference

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

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Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009720200

A role for p21-activated kinase in endothelial cell migration.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M009720200

1 reference

24 November 2017

1 reference