The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures (Q43568126)

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scientific article published in April 2001

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English	The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures	scientific article published in April 2001

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 November 2017

The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures (English)

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Europe PubMed Central

PubMed publication ID

24 November 2017

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based on heuristic

inferred from title

Morten Blaabjerg

1

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

author name string

Kristensen BW

2

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Bonde C

3

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Europe PubMed Central

PubMed publication ID

24 November 2017

Zimmer J

4

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Europe PubMed Central

PubMed publication ID

24 November 2017

language of work or name

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publication date

1 April 2001

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Europe PubMed Central

PubMed publication ID

24 November 2017

number of pages

14

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inferred from page(s)

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Europe PubMed Central

PubMed publication ID

24 November 2017

898

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Europe PubMed Central

PubMed publication ID

24 November 2017

1

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Europe PubMed Central

PubMed publication ID

24 November 2017

91-104

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Europe PubMed Central

PubMed publication ID

24 November 2017

Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide

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Pre-exposure to subtoxic levels prevents kainic acid lesions in organotypic hippocampal slice cultures: effects of kainic acid on parvalbumin-immunoreactive neurons and expression of heat shock protein 72 following the induction of tolerance

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Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells

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NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization

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Metabotropic glutamate receptor activation selectively limits excitotoxic damage in the intact neostriatum

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Proliferation and differentiation of glial fibrillary acidic protein-immunoreactive glial cells in organotypic slice cultures of rat hippocampus

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Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices.

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A submersion method to induce hypoxic damage in organotypic hippocampal cultures.

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Organotypic cultures of neural tissue

1 reference

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(1S,3R)-ACPD, a metabotropic glutamate receptor agonist, enhances damage after global ischaemia

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Functional switch from facilitation to inhibition in the control of glutamate release by metabotropic glutamate receptors.

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Adenosinergic modulation of CA1 neuronal tolerance to glucose deprivation in organotypic hippocampal cultures

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Ischemia-induced death of astrocytes and neurons in primary culture: pitfalls in quantifying neuronal cell death

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Excitotoxic effects of non-NMDA receptor agonists in organotypic corticostriatal slice cultures

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Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons

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ACPD-mediated slow-onset potentiation is associated with cell death in the rat CA1 region in vivo.

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Microtubule-associated protein 2 and tubulin are differently distributed in the dendrites of developing neurons

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Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist

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Roles of metabotropic glutamate receptors in brain plasticity and pathology

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Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes

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Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons

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Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection.

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7 January 2021

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

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Trimethyltin (TMT) neurotoxicity in organotypic rat hippocampal slice cultures

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Markers for neuronal degeneration in organotypic slice cultures

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Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

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(+)-MCPG induces PKCepsilon translocation in cortical synaptosomes through a PLD-coupled mGluR.

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1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia

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Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus

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The metabotropic glutamate receptors: structure and functions

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Spontaneous pyramidal cell death in organotypic slice cultures from rat hippocampus is prevented by glutamate receptor antagonists

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Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia

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Brain-derived neurotrophic factor, but not neurotrophin-3, prevents ischaemia-induced neuronal cell death in organotypic rat hippocampal slice cultures

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Switch from facilitation to inhibition of excitatory synaptic transmission by group I mGluR desensitization

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Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

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Comparison of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD)- and 1R,3S-ACPD-stimulated brain phosphoinositide hydrolysis

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The metabotropic glutamate receptor 1 is not involved in the facilitation of glutamate release in cerebrocortical nerve terminals

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A simple method for organotypic cultures of nervous tissue

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Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures

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Glutamate metabotropic receptor agonist 1S,3R-ACPD induces internucleosomal DNA fragmentation and cell death in rat striatum

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Cellular and connective organization of slice cultures of the rat hippocampus and fascia dentata

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10.1016/S0006-8993(01)02148-5

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Europe PubMed Central

PubMed publication ID

24 November 2017

release_mmwlru23mnfkba7iityv535xyi

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24 November 2022

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PubMed publication ID

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Europe PubMed Central

PubMed publication ID

24 November 2017

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