Excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo (Q43601575)

25 November 2017

title

Excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo (English)

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25 November 2017

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Lee SC

1

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25 November 2017

Schwarcz R

series ordinal

2

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25 November 2017

language of work or name

English

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publication date

1 May 2001

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25 November 2017

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25 November 2017

volume

304

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25 November 2017

issue

3

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25 November 2017

page(s)

185-188

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Acute and chronic changes in kynurenate formation following an intrastriatal quinolinate injection in rats

25 November 2017

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In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum

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Facilitated brain uptake of 4-chlorokynurenine and conversion to 7-chlorokynurenic acid.

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High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes

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Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus

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Enzyme-catalyzed production of the neuroprotective NMDA receptor antagonist 7-chlorokynurenic acid in the rat brain in vivo

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Identifiers

DOI

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25 November 2017

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