Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells (Q43666441)

25 November 2017

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells (English)

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25 November 2017

H P Reusch

1

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25 November 2017

S Zimmermann

2

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25 November 2017

M Schaefer

3

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25 November 2017

M Paul

4

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25 November 2017

K Moelling

5

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25 November 2017

language of work or name

English

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publication date

6 July 2001

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Journal of Biological Chemistry

25 November 2017

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25 November 2017

276

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25 November 2017

36

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25 November 2017

33630-33637

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Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty

25 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

The insulin-like growth factor system in vascular smooth muscle: interaction with insulin and growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Protein modules and signalling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Dimerization of cell surface receptors in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Preparation of functional smooth muscle cells from the rabbit aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Expression of the smooth muscle myosin heavy chain gene is regulated by a negative-acting GC-rich element located between two positive-acting serum response factor-binding elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Mechanical strain increases smooth muscle and decreases nonmuscle myosin expression in rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Gbeta gamma mediate differentiation of vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Gbetagamma stimulates phosphoinositide 3-kinase-gamma by direct interaction with two domains of the catalytic p110 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Regulator of G-protein signaling 3 (RGS3) inhibits Gbeta1gamma 2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Negative regulation of the serine/threonine kinase B-Raf by Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Phosphorylation of c-Raf-1 by protein kinase A interferes with activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Negative regulation of Raf-1 by phosphorylation of serine 621.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

The akt kinase: molecular determinants of oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Farnesylation of Ras is important for the interaction with phosphoinositide 3-kinase gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105322200

21 January 2018

Identifiers

DOI

10.1074/JBC.M105322200

1 reference

25 November 2017

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