Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities (Q43678714)

25 November 2017

Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities (English)

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25 November 2017

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Razani B

1

1 reference

25 November 2017

Engelman JA

2

1 reference

25 November 2017

Wang XB

3

1 reference

25 November 2017

Schubert W

4

1 reference

25 November 2017

Zhang XL

5

1 reference

25 November 2017

Marks CB

6

1 reference

25 November 2017

Macaluso F

7

1 reference

25 November 2017

Russell RG

8

1 reference

25 November 2017

Li M

9

1 reference

25 November 2017

Pestell RG

10

1 reference

25 November 2017

Di Vizio D

11

1 reference

25 November 2017

Hou H Jr

12

1 reference

25 November 2017

Kneitz B

13

1 reference

25 November 2017

Lagaud G

14

1 reference

25 November 2017

Christ GJ

15

1 reference

25 November 2017

Edelmann W

16

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25 November 2017

Lisanti MP

17

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25 November 2017

language of work or name

English

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publication date

16 July 2001

1 reference

Journal of Biological Chemistry

25 November 2017

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25 November 2017

276

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25 November 2017

38121-38138

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25 November 2017

41

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describes a project that uses

25 November 2017

3T3 MEFs KO

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3T3 MEFs WT

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24 May 2022

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VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro

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24 May 2022

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Three human transforming genes are related to the viral ras oncogenes

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24 May 2022

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Reduction of caveolin and caveolae in oncogenically transformed cells

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24 May 2022

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Inhibition of cyclin-dependent kinases by p21

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24 May 2022

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Reduction of caveolin-1 expression in tumorigenic human cell hybrids

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24 May 2022

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Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism

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24 May 2022

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Regulation of caveolin and caveolae by cholesterol in MDCK cells.

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24 May 2022

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Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy

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24 May 2022

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Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

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24 May 2022

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Emerging themes in lipid rafts and caveolae.

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24 May 2022

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Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

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24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Visualization of caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras. The subcellular distribution of caveolin-1 is modulated by cell-cell contact

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

INK4d-deficient mice are fertile despite testicular atrophy

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24 May 2022

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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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24 May 2022

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A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

WAF1, a potential mediator of p53 tumor suppression

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Frequent loss of heterozygosity in the region of the D7S523 locus in advanced ovarian cancer

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Downmodulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor overexpression

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Evidence for a regulated interaction between heterotrimeric G proteins and caveolin

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1)

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin is an inhibitor of platelet-derived growth factor receptor signaling

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Baculovirus-based expression of mammalian caveolin in Sf21 insect cells. A model system for the biochemical and morphological study of caveolae biogenesis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Expression and Characterization of Recombinant Caveolin

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Oligomeric structure of caveolin: implications for caveolae membrane organization

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin, a protein component of caveolae membrane coats

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

The membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for the assembly of caveolae membranes in vivo

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31).

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Fish mapping of YAC clones at human chromosomal band 7q31.2: identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Reduction of caveolin 1 gene expression in lung carcinoma cell lines

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

The fine structure of the gall bladder epithelium of the mouse.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin-2 localizes to the golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Phenotypic behavior of caveolin-3 mutations that cause autosomal dominant limb girdle muscular dystrophy (LGMD-1C). Retention of LGMD-1C caveolin-3 mutants within the golgi complex

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

A subset of p53-deficient embryos exhibit exencephaly

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Posttranslational quality control: folding, refolding, and degrading proteins.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

VIP21/caveolin is a cholesterol-binding protein

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Junctional complexes in various epithelia

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Molecular and cellular biology of caveolae paradoxes and plasticities.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Setting the standards: quality control in the secretory pathway

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Mutational analysis of caveolin-induced vesicle formation. Expression of caveolin-1 recruits caveolin-2 to caveolae membranes

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M105408200

Identifiers

DOI

10.1074/JBC.M105408200

0 references

1 reference