AAV-BDNF mediated attenuation of quinolinic acid-induced neuropathology and motor function impairment (Q43704735)

26 November 2017

AAV-BDNF mediated attenuation of quinolinic acid-induced neuropathology and motor function impairment (English)

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26 November 2017

B Connor

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author name string

A P Kells

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1

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PubMed ID

18323792

26 November 2017

R A Henry

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2

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26 November 2017

6 March 2008

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26 November 2017

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26 November 2017

15

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26 November 2017

13

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26 November 2017

966-977

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https://scigraph.springernature.com/pub.10.1038/gt.2008.23

26 November 2017

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cites work

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Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease

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Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF.

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Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease

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Lentiviral gene delivery of GDNF into the striatum of R6/2 Huntington mice fails to attenuate behavioral and neuropathological changes

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Cellular delivery of human CNTF prevents motor and cognitive dysfunction in a rodent model of Huntington's disease

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Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease.

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Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease.

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Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

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Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

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Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism.

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Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.

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Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease

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Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.

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Basal expression of the inducible transcription factors c-Jun, JunB, JunD, c-Fos, FosB, and Krox-24 in the adult rat brain

21 January 2018

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The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum.

21 January 2018

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Rotational behaviour in rats with unilateral striatal kainic acid lesions: a behavioural model for studies on intact dopamine receptors

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21 January 2018

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21 January 2018

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Verification of functional AAV-mediated neurotrophic and anti-apoptotic factor expression.

21 January 2018

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Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells

21 January 2018

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7 January 2021

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.23

7 January 2021

Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.23

7 January 2021

https://api.crossref.org/works/10.1038%2FGT.2008.23

1 reference

7 January 2021

CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury

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https://api.crossref.org/works/10.1038%2FGT.2008.23

7 January 2021

Hyperexcitability in combined entorhinal/hippocampal slices of adult rat after exposure to brain-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.23

7 January 2021

Targeted retrograde gene delivery for neuronal protection

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.23

7 January 2021

Identifiers

DOI

10.1038/GT.2008.23

1 reference

PubMed ID

18323792

Dimensions Publication ID

26 November 2017

0 references

1 reference

PubMed ID

18323792