Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection (Q43718624)

26 November 2017

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection (English)

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26 November 2017

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26 November 2017

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26 November 2017

Smythe GA

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26 November 2017

Smith DG

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26 November 2017

Kapoor V

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26 November 2017

Armati PJ

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26 November 2017

Croitoru J

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26 November 2017

Brew BJ

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26 November 2017

language of work or name

English

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publication date

1 August 2001

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Journal of Neurochemistry

26 November 2017

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26 November 2017

78

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26 November 2017

842-853

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26 November 2017

4

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A rapid method for the isolation of metabolically active mitochondria from rat neurons and astrocytes in primary culture.

26 November 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Presence of 3-hydroxyanthranilic acid in rat tissues and evidence for its production from anthranilic acid in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Kynurenine metabolism in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Induction of toxoplasmostasis in a human glioblastoma by interferon gamma

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Immunohistochemical localization of quinolinic acid phosphoribosyltransferase in the human neostriatum

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Kynurenine pathway enzymes in a rat model of chronic epilepsy: immunohistochemical study of activated glial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Uptake of 3-hydroxykynurenine measured in rat brain slices and in a neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinic acid phosphoribosyltransferase in human and rat brain: activity in Huntington's disease and in quinolinate-lesioned rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Synthesis of quinolinic acid by 3-hydroxyanthranilic acid oxygenase in rat brain tissue in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Metabolism and neuropathologic significance of quinolinic acid and kynurenic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Localization of quinolinic acid metabolizing enzymes in the rat brain. Immunohistochemical studies using antibodies to 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Immunohistochemical identification of quinolinic acid phosphoribosyltransferase in glial cultures from rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Prevention of allogeneic fetal rejection by tryptophan catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Rat 3-hydroxyanthranilic acid oxygenase: purification from the liver and immunocytochemical localization in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinic acid production by macrophages stimulated with IFN-gamma, TNF-alpha, and IFN-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Immunocytochemical localization of kynurenine aminotransferase in the rat striatum: a light and electron microscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Immunocytochemical localization of the quinolinic acid synthesizing enzyme, 3-hydroxyanthranilic acid oxygenase, in the rat substantia nigra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

3-Hydroxyanthranilate oxygenase activity is increased in the brains of Huntington disease victims

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Cerebrospinal fluid levels of quinolinic acid in Huntington's disease and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Regulation of kynurenic acid levels in the developing rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Quinolinic acid is increased in CSF and associated with mortality after traumatic brain injury in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Uptake of kynurenine into rat brain slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

On the production and disposition of quinolinic acid in rat brain and liver slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Inhibitors of the kynurenine pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Kynurenine aminotransferase I (KATI) isoform gene expression in the rat brain: an in situ hybridization study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Immunocytochemical localization of the endogenous neuroexcitotoxin quinolinate in human peripheral blood monocytes/macrophages and the effect of human T-cell lymphotropic virus type I infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

Qualitative and quantitative studies of cytokines synthesized and secreted by non-human primate peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00498.X

10.1046/J.1471-4159.2001.00498.X

21 January 2018

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release_ecwpeqq7qjfttc4uz4eueyr5pi

26 November 2017

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