The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis (Q43718785)

26 November 2017

The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis (English)

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26 November 2017

5

Rotter V

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26 November 2017

Sigal A

1

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26 November 2017

Matas D

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2

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26 November 2017

Almog N

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3

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26 November 2017

Goldfinger N

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4

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26 November 2017

language of work or name

English

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publication date

1 August 2001

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26 November 2017

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26 November 2017

20

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26 November 2017

35

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26 November 2017

4891-4898

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204724

26 November 2017

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cites work

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

The murine C'-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Immunologically distinct p53 molecules generated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

In vitro analysis of the dominant negative effect of p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Gain of function mutations in p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Allosteric activation of latent p53 tetramers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Regulation of the specific DNA binding function of p53

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Activation of the cryptic DNA binding function of mutant forms of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Small peptides activate the latent sequence-specific DNA binding function of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Oncogenic forms of p53 inhibit p53-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Activation of the insulin-like growth factor II transcription by aflatoxin B1 induced p53 mutant 249 is caused by activation of transcription complexes; implications for a gain-of-function during the formation of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Mutant p53 protein expression interferes with p53-independent apoptotic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Activation of p53 DNA binding activity by point mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Protein interactions at the carboxyl terminus of p53 result in the induction of its in vitro transactivation potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

p53-dependent cell cycle control: response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Reactivation of mutant p53: a new strategy for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Regulation of cell death by the Abl tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Augmented DNA-binding activity of p53 protein encoded by a carboxyl-terminal alternatively spliced mRNA is blocked by p53 protein encoded by the regularly spliced form

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

p53-dependent apoptosis is regulated by a C-terminally alternatively spliced form of murine p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

DNA-binding activity of wild-type p53 protein is mediated by the central part of the molecule and controlled by its C terminus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204724

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204724

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Dimensions Publication ID

26 November 2017

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