Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation. (Q43761437)

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12 November 2019

title

Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation (English)

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12 November 2019

2

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12 November 2019

author name string

Ljungman M

series ordinal

1

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12 November 2019

Paulsen MT

series ordinal

3

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12 November 2019

language of work or name

English

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publication date

1 September 2001

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12 November 2019

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12 November 2019

volume

20

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12 November 2019

issue

42

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12 November 2019

page(s)

5964-5971

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204734

12 November 2019

exact match

0 references

cites work

Stress signals utilize multiple pathways to stabilize p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

UV-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

DNA topoisomerases: essential enzymes and lethal targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Small peptides activate the latent sequence-specific DNA binding function of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Transformed cells require continuous activity of RNA polymerase II to resist oncogene-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

UV light-induced degradation of RNA polymerase II is dependent on the Cockayne's syndrome A and B proteins but not p53 or MLH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

The tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Factors associated with the mammalian RNA polymerase II holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Connecting transcription to messenger RNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Gene and transcription unit mapping by radiation effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Actinomycin and DNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Ultraviolet radiation down-regulates expression of the cell-cycle inhibitor p21WAF1/CIP1 in human cancer cells independently of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

Inhibitors of transcription, proteasome inhibitors, and DNA-damaging drugs differentially affect feedback of p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Repair in ribosomal RNA genes is deficient in xeroderma pigmentosum group C and in Cockayne's syndrome cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Inhibition of RNA polymerase II as a trigger for the p53 response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

DNA Adducts of cis-Diamminedichloroplatinum(II) and Its Trans Isomer Inhibit RNA Polymerase II Differentially in Vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Role for p300 in stabilization of p53 in the response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204734

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204734

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11593403%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 November 2019

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