DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 (Q28254119)

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7 November 2019

title

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 (English)

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7 November 2019

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1

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7 November 2019

author name string

M Ikeda

series ordinal

2

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7 November 2019

Y Taya

series ordinal

3

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7 November 2019

C Prives

series ordinal

4

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7 November 2019

language of work or name

English

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publication date

1 October 1997

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7 November 2019

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7 November 2019

volume

91

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7 November 2019

page(s)

325-334

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7 November 2019

issue

3

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Recruitment of p300/CBP in p53-dependent signal pathways

7 November 2019

cites work

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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A DNA-activated protein kinase from HeLa cell nuclei

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7 January 2021

Mapping of the p53 and mdm-2 interaction domains

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Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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Wild-type p53 activates transcription in vitro

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DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

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7 January 2021

The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.

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7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

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Synergistic activation of transcription by CBP and p53

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V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

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p53 induction, cell cycle checkpoints, and apoptosis in DNAPK-deficient scid mice.

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases

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7 January 2021

Regulation of the specific DNA binding function of p53

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7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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7 January 2021

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

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7 January 2021

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

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7 January 2021

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

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7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Binding and modulation of p53 by p300/CBP coactivators

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7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

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7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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7 January 2021

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

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7 January 2021

p53 Phosphorylation: biochemical and functional consequences

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

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7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

894690

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

894690

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

894690