Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: dose-dependent pharmacokinetics in rats. (Q43768917)

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12 November 2019

title

Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: dose-dependent pharmacokinetics in rats (English)

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12 November 2019

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2

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12 November 2019

author name string

X Zhang

series ordinal

1

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12 November 2019

language of work or name

English

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publication date

1 October 2001

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International Journal of Pharmaceutics

12 November 2019

published in

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12 November 2019

volume

229

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12 November 2019

issue

1-2

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12 November 2019

page(s)

173-182

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Physiologic modeling of cyclosporin kinetics in rat and man.

12 November 2019

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Macromolecular prodrugs. XV. Colon-targeted delivery--bioavailability of naproxen from orally administered dextran-naproxen ester prodrugs varying in molecular size in the pig

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Macromolecular prodrugs. XVI. Colon-targeted delivery--comparison of the rate of release of naproxen from dextran ester prodrugs in homogenates of various segments of the pig gastrointestinal (GI) tract

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Glucocorticoid-dextran conjugates as potential prodrugs for colon-specific delivery: hydrolysis in rat gastrointestinal tract contents

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Simultaneous analysis of dextran-methylprednisolone succinate, methylprednisolone succinate, and methylprednisolone by size-exclusion chromatography

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High-performance size-exclusion chromatographic analysis of dextran-methylprednisolone hemisuccinate in rat plasma.

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Kinetics of hydrolysis of dextran-methylprednisolone succinate, a macromolecular prodrug of methylprednisolone, in rat blood and liver lysosomes

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Simultaneous analysis of methylprednisolone, methylprednisolone succinate, and endogenous corticosterone in rat plasma

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Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: immunosuppressive effects after in vivo administration to rats

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Molecular weight dependent tissue accumulation of dextrans: in vivo studies in rats

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Dose dependency of the kinetics of dextrans in rats: effects of molecular weight

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Molecular-weight-dependent pharmacokinetics of fluorescein-labeled dextrans in rats

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Multiple pathways for ligand internalization in rat hepatocytes II: Effect of hyperosmolarity and contribution of fluid-phase endocytosis

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Fluid endocytosis by rat liver and spleen. Experiments with 125I-labelled poly(vinylpyrrolidone) in vivo

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Demonstration of the receptor-mediated hepatic uptake of dextran in mice

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Hydrolysis of methylprednisolone hemisuccinate to methylprednisolone by a nonspecific carboxylesterase

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Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: in vitro immunosuppressive effects on rat blood and spleen lymphocytes

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The splitting of dextran and isomaltose by animal tissues

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A quantitative study of fluorescein isothiocyanate-dextran transport in the microcirculation of the isolated perfused rat liver

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Macromolecular drug carrier systems in cancer chemotherapy: macromolecular prodrugs

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7 January 2021

10.1016/S0378-5173(01)00854-7

Identifiers

DOI

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12 November 2019

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