Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells (Q43821776)

27 November 2017

Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells (English)

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27 November 2017

Lakey JR

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27 November 2017

Suarez-Pinzon WL

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27 November 2017

Strynadka K

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27 November 2017

Korbutt GS

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27 November 2017

Rajotte RV

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27 November 2017

Mabley JG

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27 November 2017

Szabó C

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27 November 2017

Rabinovitch A

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27 November 2017

1 December 2001

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27 November 2017

Laboratory Investigation

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27 November 2017

81

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27 November 2017

12

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27 November 2017

1683-1692

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https://scigraph.springernature.com/pub.10.1038/labinvest.3780381

27 November 2017

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cites work

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Adenovirus-mediated catalase gene transfer reduces oxidant stress in human, porcine and rat pancreatic islets

21 January 2018

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

21 January 2018

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Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

21 January 2018

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Antioxidant enzyme activities in IDD-prone and IDD-resistant mice: a comparative study.

21 January 2018

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Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells

21 January 2018

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Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

21 January 2018

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CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse.

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

21 January 2018

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Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

21 January 2018

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Targeted overexpression of Cu/Zn superoxide dismutase protects pancreatic beta-cells against oxidative stress

21 January 2018

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Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes

21 January 2018

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Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

21 January 2018

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Peroxynitrite-induced apoptosis in HL-60 cells

21 January 2018

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Determinants of the selective toxicity of alloxan to the pancreatic B cell

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

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Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction

21 January 2018

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Automated method for isolation of human pancreatic islets

21 January 2018

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21 January 2018

An improved MTT assay.

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An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice

21 January 2018

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Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.

21 January 2018

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Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform

21 January 2018

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Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

21 January 2018

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Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss

21 January 2018

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7 January 2021

Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation

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7 January 2021

Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death

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7 January 2021

Experimental procedure for a hydrogen peroxide assay based on the peroxidase-oxidase reaction

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7 January 2021

Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

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7 January 2021

Quantitation of protein-bound 3-nitrotyrosine and 3,4-dihydroxyphenylalanine by high-performance liquid chromatography with electrochemical array detection

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7 January 2021

Sensitive determination of nitrotyrosine in human plasma by isocratic high-performance liquid chromatography

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7 January 2021

Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.

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7 January 2021

Contribution of adenoviral-mediated superoxide dismutase gene transfer to the reduction in nitric oxide-induced cytotoxicity on human islets and INS-1 insulin-secreting cells

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7 January 2021

Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

Cytotoxic effect of IFN-gamma plus TNF-alpha on human islet cells

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.

1 reference

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7 January 2021

Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

Overexpression of catalase provides partial protection to transgenic mouse beta cells

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780381

7 January 2021

10.1038/LABINVEST.3780381

Identifiers

DOI

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27 November 2017

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