Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans (Q24314701)

Interferon gamma

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nitric oxide synthase 2

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tumor necrosis factor d1

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regulation of insulin secretion

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J A Corbett

1

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M A Sweetland

2

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J L Wang

3

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J R Lancaster

4

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M L McDaniel

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

1 March 1993

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published in

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volume

90

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page(s)

1731-5

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issue

5

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cites work

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Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

19 March 2017

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Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein

27 September 2017

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Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy

27 September 2017

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Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

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Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide

27 September 2017

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Interaction of beta-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans.

27 September 2017

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Interleukin 1 is potent modulator of insulin secretion from isolated rat islets of Langerhans

27 September 2017

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IFN-gamma-activated macrophages: detection by electron paramagnetic resonance of complexes between L-arginine-derived nitric oxide and non-heme iron proteins

30 May 2018

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Nitrogen oxide levels in patients after trauma and during sepsis

30 May 2018

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L-Arginine Stimulates Cyclic Guanosine 3′,5′- Monophosphate Formation in Rat Islets of Langerhans and RINm5F Insulinoma Cells: Evidence for LArgininerNitric Oxide Synthase*

30 May 2018

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Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages.

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Nitric oxide production by monocytes in alcoholic liver disease

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Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction

30 May 2018

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Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction

30 May 2018

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Increased circulating nitrogen oxides after human tumor immunotherapy: correlation with toxic hemodynamic changes

30 May 2018

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Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides

30 May 2018

1 reference

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Adoptive transfer of autoimmune diabetes mellitus in biobreeding/Worcester (BB/W) inbred and hybrid rats.

30 May 2018

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Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

30 May 2018

1 reference

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Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation

29 November 2018

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12 December 2020

Pathologic anatomy of the pancreas in juvenile diabetes mellitus

1 reference

12 December 2020

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

1 reference

12 December 2020

Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice

1 reference

12 December 2020

Low-temperature culture of human islets isolated by the distention method and purified with Ficoll or Percoll gradients

1 reference

12 December 2020

Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism

1 reference

12 December 2020

Inhibition of nitric oxide generation affects the induction of diabetes by streptozocin in mice

1 reference

12 December 2020

Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion

1 reference

12 December 2020

Biological roles of nitric oxide

1 reference

12 December 2020

Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation

1 reference

12 December 2020

Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase*

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.5.1731

1 reference

2655517

ADS bibcode

1993PNAS...90.1731C

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2655517

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1 reference

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