Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954. (Q43831003)

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5 December 2019

title

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954 (English)

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5 December 2019

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2

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5 December 2019

Rosalind Glasspool

5

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5 December 2019

author name string

Plumb JA

1

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5 December 2019

Kakani R

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5 December 2019

Zhao J

4

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5 December 2019

Knox RJ

6

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5 December 2019

Evans TR

7

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5 December 2019

Keith WN

8

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5 December 2019

language of work or name

English

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publication date

1 November 2001

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5 December 2019

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5 December 2019

volume

20

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5 December 2019

issue

53

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5 December 2019

page(s)

7797-7803

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204954

5 December 2019

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cites work

Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Nitroreductase activation of CB1954--an alternative 'suicide' gene system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Mechanism-based target identification and drug discovery in cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Gene directed enzyme/prodrug therapy of cancer: historical appraisal and future prospectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Transcriptional control: an essential component of cancer gene therapy strategies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Gene therapy: designer promoters for tumour targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Is small cell lung cancer the perfect target for anti-telomerase treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Preclinical and clinical strategies for development of telomerase and telomere inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

21 January 2018

Telomerase and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Telomerase in cancer: clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Strategies for achieving multiple layers of selectivity in gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

21 January 2018

Telomerase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Activation of telomerase rna gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Cloning and characterization of human and mouse telomerase RNA gene promoter sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

Demonstration of constant upregulation of the telomerase RNA component in human gastric carcinomas using in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

7 January 2021

The RNA component of telomerase as a marker of biologic potential and clinical outcome in childhood neuroblastic tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

7 January 2021

Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

7 January 2021

Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

7 January 2021

Catalytic subunit of telomerase expression is related to RNA component expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204954

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204954

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11753658%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 December 2019

0 references

1 reference