The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts (Q43832310)

27 November 2017

title

The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts (English)

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27 November 2017

1

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27 November 2017

Bieler CA

2

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27 November 2017

Wiessler M

series ordinal

3

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27 November 2017

Frei E

series ordinal

4

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27 November 2017

language of work or name

English

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publication date

1 December 2001

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27 November 2017

published in

Biochemical Pharmacology

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27 November 2017

volume

62

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27 November 2017

issue

12

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27 November 2017

page(s)

1675-1684

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Data of pre-clinical and early clinical trials of acriflavine and hydroxy-methyl-ellipticine reviewed, enriched by the experience of their use for 18 months to 6 years in combinations with other HIV1 virostatics

27 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Anticancer specificity of some ellipticinium salts against human brain tumors in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Preclinical evaluation of 9-chloro-2-methylellipticinium acetate alone and in combination with conventional anticancer drugs for the treatment of human brain tumor xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Synthesis and binding properties to DNA and to opioid receptors of enkephalin-ellipticinium conjugates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Cytotoxic agents directed to peptide hormone receptors: defining the requirements for a successful drug

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Multimodal action of antitumor agents on DNA: the ellipticine series

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Ellipticines and human liver microsomes: spectral interaction with cytochrome P-450 and hydroxylation. Inhibition of aryl hydrocarbon metabolism and mutagenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Molecular analysis of mutations induced by the intercalating agent ellipticine at the hisD3052 allele of Salmonella typhimurium TA98.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Analysis of structural requirements for Ah receptor antagonist activity: ellipticines, flavones, and related compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Constitutive activation of the aromatic hydrocarbon receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Mutagenicity of topoisomerase-active agents in bacteriophage T4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Tests for the genotoxicity of m-AMSA, etoposide, teniposide and ellipticine in Neurospora crassa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Comparison of the mutagenic responses of 12 anticancer drugs at the hypoxanthine-guanine phosphoribosyl transferase and adenosine kinase loci in chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Prophage induction by DNA topoisomerase II poisons and reactive-oxygen species: role of DNA breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

High-field NMR and restrained molecular modeling studies on a DNA heteroduplex containing a modified apurinic abasic site in the form of covalently linked 9-aminoellipticine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Ellipticine increases the superhelical density of intracellular SV40 DNA by intercalation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Inhibition of p53 Protein Phosphorylation by 9‐Hydroxyellipticine: A Possible Anticancer Mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Protonophoric activity of ellipticine and isomers across the energy-transducing membrane of mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Expression of xenobiotic metabolizing enzymes in breast cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

The immunohistochemical localization of drug-metabolizing enzymes in prostate cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Comparison of DNA adduct formation by aristolochic acids in various in vitro activation systems by 32P-post-labelling: evidence for reductive activation by peroxidases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Mechanism of formation and 32P-postlabeling of DNA adducts derived from peroxidative activation of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Benzenediazonium ion derived from Sudan I forms an 8-(phenylazo)guanine adduct in DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

New Selective Inhibitors of Cytochrome P450 2B4 and an Activator of Cytochrome P450 3A6 in Rabbit Liver Microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

32P-postlabeling analysis of non-radioactive aromatic carcinogen--DNA adducts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

32P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement procedures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

DNA adduct formation of aristolochic acid I and II in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Interactions between cytochrome P450 and cytochrome b5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Peroxidase-catalyzed covalent binding of the antitumor drug N2-methyl-9-hydroxyellipticinium to DNA in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobiotics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900806-1

10.1016/S0006-2952(01)00806-1

7 January 2021

Identifiers

DOI

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27 November 2017

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